Results 31 to 40 of about 29,245 (266)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
KIT MOMA: A Mobile Machines Dataset
CoRR, 2020 Mobile machines typically working in a closed site, have a high potential to utilize autonomous driving technology. However, vigorously thriving development and innovation are happening mostly in the area of passenger cars. In contrast, although there are also many research pieces about autonomous driving or working in mobile machines, a consensus ...
Yusheng Xiang +6 more
openaire +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Evolution of machine intelligence for mobile robot.
Journal of the Robotics Society of Japan, 1988 Active research and development is carried out for various mobile robots or robotic vehicles. This paper tries to find a new principle of the evolution of machine intelligence for robotic vehicles. The machine intelligence of robotic vehicles is the integrated ability composed of sensors, actuators, and computers, which produces the travel versatility ...
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
MULTISENSOR EQUIPPED UAV/UGV FOR AUTOMATED EXPLORATION [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2017 The usage of unmanned systems for exploring disaster scenarios has become more and more important in recent times as a supporting system for action forces.
S. Batzdorfer +4 more
doaj +1 more source
A machine-learning approach to a mobility policy proposal
Heliyon, 2023 The objective of the URBANITE project is to design an open-data, open-source, smart-city framework to enhance the decision-making processes in European cities. The framework's basis is a robust and user-friendly simulation tool that is supplemented with several innovative service modules.
Shulajkovska, Miljana +3 more
openaire +4 more sources
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source