Results 51 to 60 of about 613,590 (287)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

TODAY'S CITIES: CHALLENGES FOR REHABILITATION NURSES FOR INCLUSION

Revista Portuguesa de Enfermagem de Reabilitação, 2020
The architectural barriers on public highway cause inaccessibility, contributing to the limitation of functionality and creation of disability. Objectives: to analyze the conditions of accessibility on public highways in view of the needs of disabled ...
Ana Isabel Ribeiro Da Silva Pereira, Maria Manuela Ferreira Pereira Da Silva Martins, Rute Salomé da Silva Pereira, Bárbara Pereira Gomes, João Santos, Paulo Alexandre Matos Cunha   +5 more
doaj   +1 more source

Controlling for endogeneity in the health-socioeconomic status relationship of the near retired [PDF]

, 2009
Copyright 2009 Elsevier B.V., All rights reserved.Peer ...
Bender, Keith A, Theodossiou, Ioannis
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Electronic structure and transport in amorphous metal oxide and amorphous metal oxy-nitride semiconductors

, 2019
Recently amorphous oxide semiconductors (AOS) have gained commercial interest due to their low-temperature processability, high mobility and areal uniformity for display backplanes and other large area applications. A multi-cation amorphous oxide (a-IGZO)
Bhowmick, Somnath, Gaur, Anshu, Nahas, Suhas, Srivastava, Juhi   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Effect of Short-Term Conditional-Equilibrium Exercises on Balance and Functional Limitations in Aged Women With Frailty Syndrome: A Randomized Controlled Trail

Sālmand, 2022
Objectives Increasing frailty syndrome is one consequence of the aging population. Frailty syndrome can adversely affect the independent life and social activities of the elderly by threatening their balance and mobility.
Foruzan Tavan, Mahsa Yarelahi, Negin Chehrehnegar, Abdolrahim Asadollahi   +3 more
doaj  

Making On-Demand Routing Efficient with Route-Request Aggregation

, 2016
In theory, on-demand routing is very attractive for mobile ad hoc networks (MANET), because it induces signaling only for those destinations for which there is data traffic.
Garcia-Luna-Aceves J.J., Mohapatra P., Mosko M., Pei G., Raju J., Rangarajan H., Roy S., Royer E., Shiflet C., Wang Y.   +9 more
core   +1 more source

Diffusion as a First Model of Spread of Viral Infection

, 2020
The appearance of the coronavirus (COVID-19) in late 2019 has dominated the news in the last few months as it developed into a pandemic. In many mathematics and physics classrooms, instructors are using the time series of the number of cases to show ...
Acioli, Paulo H.
core   +1 more source

Low strength is related to diminished ground reaction forces and walking performance in older women [PDF]

, 2011
The purpose of this study was to determine how lower-limb strength in older women affected gait speed, supportive forces, spatial, and temporal aspects of walking gait.
Kralian, Rachel J., LaRoche, Dain P., Millet, Erica D.   +2 more
core   +2 more sources