Results 51 to 60 of about 165,746 (253)
ABSTRACT Introduction Anthracycline‐related cardiac remodeling precedes heart failure in childhood cancer survivors. The objectives of this study were to determine the relationships between patient‐specific factors, moderate‐to‐vigorous physical activity (MVPA), and cardiac remodeling.
Hari K. Narayan +15 more
wiley +1 more source
Objectives Increasing frailty syndrome is one consequence of the aging population. Frailty syndrome can adversely affect the independent life and social activities of the elderly by threatening their balance and mobility.
Foruzan Tavan +3 more
doaj
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
Deciphering Predictability Limits in Human Mobility [PDF]
Human mobility has been studied from different perspectives. One approach addresses predictability, deriving theoretical limits on the accuracy that any prediction model can achieve in a given dataset. This approach focuses on the inherent nature and fundamental patterns of human behavior captured in the dataset, filtering out factors that depend on ...
Teixeira, Douglas +3 more
openaire +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Isabel Fialho Fontenele Garcia,1 Carina Tiemi Tiuganji,1 Maria do Socorro Morais Pereira Simões,2 Adriana Claudia Lunardi1,3 1Master’s and Doctoral, Programs in Physical Therapy, Universidade Cidade de São Paulo, São Paulo, SP,
Garcia IFF +3 more
doaj
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A refined limit on the predictability of human mobility [PDF]
It has been recently claimed that human movement is highly predictable. While an upper bound of 93% predictability was shown, this was based upon human movement trajectories of very high spatiotemporal granularity. Recent studies reduced this spatiotemporal granularity down to the level of GPS data, and under a similar methodology results once again ...
Gavin Smith +3 more
openaire +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Introduction: Functional movement screen (FMS), a seven-test battery, has been introduced to identify individuals at risk of injury. It is sometimes impossible to use the whole FMS battery, due to the limitations of time or resources.
Mustafa Ziaei, Vahid Zolaktaf
doaj +1 more source

