Results 51 to 60 of about 1,429,953 (284)

TODAY'S CITIES: CHALLENGES FOR REHABILITATION NURSES FOR INCLUSION

Revista Portuguesa de Enfermagem de Reabilitação, 2020
The architectural barriers on public highway cause inaccessibility, contributing to the limitation of functionality and creation of disability. Objectives: to analyze the conditions of accessibility on public highways in view of the needs of disabled ...
Ana Isabel Ribeiro Da Silva Pereira, Maria Manuela Ferreira Pereira Da Silva Martins, Rute Salomé da Silva Pereira, Bárbara Pereira Gomes, João Santos, Paulo Alexandre Matos Cunha   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Towards a core-set of mobility measures in ageing research: The need to define mobility and its constructs

BMC Geriatrics, 2023
Background Mobility is a key determinant and outcome of healthy ageing but its definition, conceptual framework and underlying constructs within the physical domain may need clarification for data comparison and sharing in ageing research.
Esmee M. Reijnierse, Sven J.G. Geelen, Marike van der Schaaf, Bart Visser, Rob C.I. Wüst, Mirjam Pijnappels, Carel G. M. Meskers   +6 more
doaj   +1 more source

Using the cell phone while standing or walking affects balance and mobility in people with Parkinson's disease

Arquivos de Neuro-Psiquiatria, 2023
Background Cell phones are part of peoples' lives. The literature indicates risks when cell phones are used during a secondary motor task. Studies addressing this topic in people with Parkinson's disease are still scarce.
Tayla Borges Lino, Milena Nunes de Oliveira da Silva, Isabela Corrêa de Paula, Sarah Jane Lemos de Melo, Suzi Rosa Miziara Barbosa, Gustavo Christofoletti   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

SESSÃO ÚNICA DE REALIDADE VIRTUAL NÃO TÊM EFEITO SOBRE MOBILIDADE FUNCIONAL EM PACIENTES COM COVID-19 INTERNADOS EM UNIDADE DE TERAPIA INTENSIVA

Sağlık Akademisi Kastamonu, 2022
Introdução: A pandemia da doença coronavírus 2019 (COVID-19), acomete em sua maioria o sistema respiratório, além de disfunções em outros sistemas do organismo, evoluindo com complicações graves, o que resulta em necessidade de cuidados intensivos.
Juliana Carvalho Schleder, Maurício Zadra Pacheco, Débora Melo Mazzo, Eduardo Manoel De Lara, Elaine Becher Santos, Talita Wassmuth   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Mobile people, mobile measures: Limitations and opportunities for mobility analysis

, 2012
As the third in a (now) regular round of National Aboriginal and Torres Strait Islander Social Surveys (NATSISS), the 2008 survey is an important addition to the ever-growing armoury of statistical information available to governments and others in their analysis of the social, cultural and economic circumstances of Indigenous Australians.
Taylor, John, Bell, Martin J.
openaire   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source