Results 91 to 100 of about 7,733 (194)

Modafinil Induced Psychosis in a Patient with Recurrent Depressive Disorder: A Case Report

open access: yesKerala Journal of Psychiatry
BACKGROUND: Modafinil is the first FDA-designated “wakefulness-promoting agent” and is approved for use as an adjuvant in mood disorders. In depressive disorders, it is reported to be effective in alleviating fatigue and related symptoms. The molecule is
Gopika SS   +2 more
doaj   +1 more source

Caracterização experimental da sensibilização comportamental "imediata" ao modafinil em camundongos

open access: yes, 2015
Há grande controvérsia sobre o potencial de abuso do modafinil, uma droga aprovada para o tratamento da narcolepsia, estudada como possível agente terapêutico para o tratamento da dependência por cocaína, e utilizada de modo indiscriminado por indivíduos
Wuo-Silva, Raphael [UNIFESP]
core  

Modafinil for multiple sclerosis fatigue: does it work?

open access: yes, 2010
UNLABELLED: Modafinil is sometimes used in the clinical setting for treating multiple sclerosis (MS) fatigue, despite conflicting and disappointing results from clinical trials.
Palace, J   +3 more
core   +1 more source

Perceived cognitive performance in off‐prescription users of modafinil and methylphenidate: an online survey

open access: yesBrain and Behavior
Introduction Modafinil and methylphenidate are used off‐prescription for cognitive enhancement in healthy individuals. Such use is often reported in online surveys but it is unclear whether drug use for cognitive enhancement is motivated by perceived ...
Rachel D. Teodorini   +2 more
doaj   +1 more source

Motor excitability and motor behaviour after modafinil ingestion

open access: yes, 2004
Die Hauptwirkung von Modafinil besteht in der Steigerung der Wachheit, wobei der genaue Wirkmechanismus noch zu klären ist. Modafinil ist bei Narkolepsie mit und ohne Kataplexie zugelassen.
Allstadt-Schmitz, Julia
core  

Pharmacologie du Modafinil et revue bibliographique

open access: yes, 1996
Le modafinil, par son mode d'action original, ne peut pas être classé dans la classe des nooanaleptiques, qu'ils soient amphétaminiques (type déxamphétamine), ou non amphétaminiques (type méthylphénidate). Il appartient à une nouvelle famille de molécule
Torregrossa, Patricia
core  

Modafinil in the media : metaphors, medicalisation and the body

open access: yes, 2009
This paper uses UK media coverage of the sleep drug modafinil to investigate the medicalisation of sleep at a conceptual level. Using metaphorical frame analysis we investigate the conceptual links created in media discourse between sleep and health, and
Coveney, Catherine M.   +6 more
core   +1 more source

Modafinil inhibits rat midbrain dopaminergic neurons through D2-like receptors.

open access: yes, 2007
International audienceModafinil is a well-tolerated medication for excessive sleepiness, attention-deficit disorder, cocaine dependence and as an adjunct to antidepressants with low propensity for abuse. We investigated the modafinil action on identified
Lin, Jian-Sheng   +5 more
core   +1 more source

Treatment of idiopathic hypersomnia with modafinil in an individual at clinical high risk for psychosis: A case report

open access: yesPCN Reports
Background Recent studies have shown that sleep disturbances are frequent at different stages of psychosis, including clinical high risk for psychosis (CHR‐P). However, the comorbidity of hypersomnia with CHR‐P and its treatment have rarely been reported
Yutaro Sato   +2 more
doaj   +1 more source

The Structural Basis of the Activity Cliff in Modafinil-Based Dopamine Transporter Inhibitors

open access: yesBiomolecules
Modafinil analogs with either a sulfoxide or sulfide moiety have improved binding affinities at the human dopamine transporter (hDAT) compared to modafinil, with lead sulfoxide-substituted analogs showing characteristics of atypical inhibition (e.g ...
Kuo-Hao Lee   +3 more
doaj   +1 more source

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