Results 71 to 80 of about 118,827 (219)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Detection of Material Degradation of a Composite Cylinder Using Mode Shapes and Convolutional Neural Networks. [PDF]
Materials (Basel), 2021 Miller B, Ziemiański L.
europepmc +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Identification of Mode Shapes of a Composite Cylinder Using Convolutional Neural Networks. [PDF]
Materials (Basel), 2021 Miller B, Ziemiański L.
europepmc +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Assessment of Internal Damage in Sandwich Structures by Post-Processing of Mode Shapes Using Curvelet Transform. [PDF]
Materials (Basel), 2021 Katunin A, Ručevskis S.
europepmc +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Applied SciencesThis study proposes a simplified approach for the experimental dynamic characterization of the historic Messina Bell Tower (northeastern Sicily) using passive seismic single-station surveys.
Sabrina Grassi +2 more
doaj +1 more source
Effects of Cable on the Dynamics of a Cantilever Beam with Tip Mass
Shock and Vibration, 2016 The dynamic effects of cable attachment on a cantilever beam with tip mass are investigated by an improved Chebyshev spectral element method. The cabled beam is modeled as a double-beam system connected by springs at several discrete locations.
Yi-Xin Huang, Hao Tian, Yang Zhao
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source