Results 51 to 60 of about 3,497,010 (299)

Characterizing Efficacy of Alternative Media for Requirements Expression

Systems
Requirements are most commonly expressed in natural language, but alternative media can be employed. Previous research has established the viability of model diagrams and engineering drawings for requirements expression.
Jason Kolligs, Lawrence Dale Thomas
doaj   +1 more source

An Approach to Complement Model-Based Vehicle Development by Implementing Future Scenarios

World Electric Vehicle Journal, 2021
Today, vehicle development is already in a process of substantial transformation. Mobility trends can be derived from global megatrends and have a significant influence on the requirements of the developed vehicles.
Christian Raulf, Moritz Proff, Tobias Huth, Thomas Vietor   +3 more
doaj   +1 more source

Model-based simulation systems engineering

, 2018
Synergien spielen eine entscheidende Rolle in der Entwicklung der Simulationsdisziplin. Der Beitrag des Fachbereichs Systems Engineering zur Simulation besteht in der Einführung von Methoden, die das Engineering von Simulationen speziell für große und komplexe Systeme verbessern.
openaire   +2 more sources

Model-Based Systems Engineering for Systems Simulation [PDF]

, 2018
Model-Based Systems Engineering and early simulation based Validation & Verification are now key enablers for managing the complexity in the development of modern complex systems like Cyber-Physical Systems. Models provide a formal account of system requirements and design decisions.
Leroux-Beaudout, Renan, Pantel, Marc, Ober, Ileana, Bruel, Jean-Michel   +3 more
openaire   +2 more sources

A Model-Based Approach for Requirements Engineering for Systems of Systems [PDF]

, 2015
Model-based systems engineering (MBSE) is a discipline of systems engineering in which the model forms the heart of all the systems engineering activities and is the basis of many of the project artefacts. Systems modeling is no longer viewed as simply a
Bryans, J., Hallerstede, S., Hansen, F.O., Holt, J., Payne, R., Perry, S.   +5 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

MODEL BASED SYSTEMS ENGINEERING INTRODUCTION WITHIN INDUSTRIAL ENGINEERING CURRICULUM

DS 95: Proceedings of the 21st International Conference on Engineering and Product Design Education (E&PDE 2019), University of Strathclyde, Glasgow. 12th -13th September 2019, 2019
Systems Engineering (SE) has been initially developed to manage large complex system development in the defence or aerospace industry. As the complexity of product increases, the product development approaches evolved accordingly. Complex architectures have to be developed including multiple disciplines of engineering (software, electronics, mechanics ...
David, Pierre, Blanco, Eric, Revol, Sebastien, Noyrit, Florian, Coatrine, Michel   +4 more
openaire   +3 more sources

A Methodology to Engineer and Validate Dynamic Multi-level Multi-agent Based Simulations

, 2013
This article proposes a methodology to model and simulate complex systems, based on IRM4MLS, a generic agent-based meta-model able to deal with multi-level systems.
C. Chen, D. Weyns, D.-A. Vo, F. Michel, F. Michel, G. Morvan, H. Brussel Van, J. Gil-Quijano, N. Gaud, T. Moncion   +9 more
core   +1 more source

A synthesis of logic and biology in the design of dependable systems [PDF]

, 2015
The technologies of model-based design and dependability analysis in the design of dependable systems, including software intensive systems, have advanced in recent years.
Papadopoulos, Yiannis
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source