Results 91 to 100 of about 4,928,263 (304)
INDIeAuthor: A Metamodel-Based Textual Language for Authoring Educational Courses
IEEE Access, 2019 This paper presents the INDIeAuthor authoring tool, which has been developed at the Digital Content Production Center, Polytechnic University of Cartagena (UPCT).
Daniel Perez-Berenguer +1 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Edge IoT Prototyping Using Model-Driven Representations: A Use Case for Smart Agriculture
SensorsIndustry 4.0 is positioned at the junction of different disciplines, aiming to re-engineer processes and improve effectiveness and efficiency. It is taking over many industries whose traditional practices are being disrupted by advances in technology and
Ivan Guevara +4 more
doaj +1 more source
Simulation of Road Traffic Applying Model-Driven Engineering
Advances in Distributed Computing and Artificial Intelligence Journal, 2016 Road traffic is an important phenomenon in modern societies. The study of its different aspects in the multiple scenarios where it happens is relevant for a huge number of problems.
Alberto FERNÁNDEZ-ISABEL +1 more
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Scale Modular Test Platform for the Characterization of PD Measuring Systems Using HFCT Sensors
SensorsToday, online partial discharge (PD) measurements are common practice to assess the condition status of dielectrics in high-voltage (HV) electrical grids.
Eduardo Arcones +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Usability evaluation of the domain specific language for spatial simulation scenarios
Cogent Engineering, 2018 This article presents the results of a usability evaluation initiative conducted on the Domain Specific Language for Spatial Simulation Scenarios (short name DSL3S) and its supporting tools.
Luís Moreira de Sousa +1 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Model-Driven Software Development
, 2019 Smartphones sind aus dem Alltag nicht mehr wegzudenken und das Ökosystem mobiler Apps wächst kontinuierlich. Dieser Trend wird durch das Aufkommen neuer mobiler Geräte oder Wearables verstärkt und auch weitere Geräte wie Smart-TVs sind appfähig geworden.
openaire +2 more sources