Results 101 to 110 of about 952,227 (243)
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
A brief introduction to model-driven engineering
Tecnura, 2014 La crisis del software es un concepto que comenzó a utilizarse en 1968, en la primera conferencia organizada por la Organización del Tratado del Atlántico Norte (OTAN) en el desarrollo de software.
Vicente García Díaz +5 more
doaj
Automatic PLC Control Logic Generation Method Based on SysML System Design Model
ActuatorsAutomatic generation of Programmable Logic Controller (PLC) programs from system design models can reduce system development costs and shorten system development cycles. However, effective methods for ensuring the quality and performance of control logic
Bo Ling, Changyong Chu, Chuan Xu
doaj +1 more source
Agile Model Driven Development of Electronic Health Record-Based Specialty Population Registries. [PDF]
IEEE EMBS Int Conf Biomed Health Inform, 2016 Kannan V, Fish JC, Willett DL.
europepmc +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
LocSys: A Low-Code Paradigm for the Development of Cyber-Physical Applications
SensorsApplication development for the cyber-physical systems (CPS) domain is considered a quite complex procedure, since it not only requires a high level of expertise but also deep knowledge of heterogeneous domains.
Konstantinos Panayiotou +2 more
doaj +1 more source
Archetype Model-Driven Development Framework for EHR Web System. [PDF]
Healthc Inform Res, 2013 Kobayashi S, Kimura E, Ishihara K.
europepmc +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
UML-based Model Driven Development
, 2018 The Unified Modeling Language (UML) is the “de jure” and “de facto” standard modeling language for software systems. It has been updated regularly since its inception, is being taught in universities all over the world and has been used extensively as a basis for Model-Driven Development (MDD) research initiatives.
openaire +1 more source