Results 71 to 80 of about 1,736,997 (282)

Traceability for Model Driven, Software Product Line Engineering [PDF]

, 2008
Traceability is an important challenge for software organizations. This is true for traditional software development and even more so in new approaches that introduce more variety of artefacts such as Model Driven development or Software Product Lines ...
Anquetil, N., Arboleda, H., Galvao Lourenco da Silva, I., Garcia, A., Grammel, B., Noppen, J.A.R., Rashid, A., Shakil Khan, S.   +7 more
core   +5 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Category Theory and Model-Driven Engineering: From Formal Semantics to Design Patterns and Beyond

, 2012
There is a hidden intrigue in the title. CT is one of the most abstract mathematical disciplines, sometimes nicknamed "abstract nonsense". MDE is a recent trend in software development, industrially supported by standards, tools, and the status of a new "
Antkiewicz, Batory, Bernstein, Bohannon, Boronat, Czarnecki, Diskin, Diskin, Diskin, Diskin, Diskin, Diskin, Diskin, Diskin, Diskin, Diskin, Diskin, Diskin, Diskin, Ehrig, Fiadeiro, Fiadeiro, Fiadeiro, Fiadeiro, Foster, Goguen, Hermann, Hofmann, Johnson, Johnson, Johnson, Johnson, José Fiadeiro, Jurack, Liang, Makkai, Matsuda, Pottinger, Rossini, Rossini, Rutle, Rutle, Selic, Shaw, Spaccapietra, Stevens, Thomas Soboll, Tom Maibaum, Ulrike Golas, Xiong, Zinovy Diskin   +50 more
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Agile Development of PHP Websites: A Model-Aware Approach

Complex Systems Informatics and Modeling Quarterly, 2020
The Design Science research method was hereby employed to develop an artifact that demonstrates the experimental “model-aware” software engineering methodology in the context of PHP Web development – a “low code” development approach with code templates ...
Carmen Ioana Gog
doaj   +1 more source

Model-driven engineering approach to design and implementation of robot control system [PDF]

, 2013
In this paper we apply a model-driven engineering approach to designing domain-specific solutions for robot control system development. We present a case study of the complete process, including identification of the domain meta-model, graphical notation
Trojanek, Piotr
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

A brief introduction to model-driven engineering

Tecnura, 2014
La crisis del software es un concepto que comenzó a utilizarse en 1968, en la primera conferencia organizada por la Organización del Tratado del Atlántico Norte (OTAN) en el desarrollo de software.
Vicente García Díaz, Edward Rolando Nüñez Valdez, Jordán Pascual Espada, B. Cristina Pelayo García Bustelo, Juan Manuel Cueva Lovelle, Carlos Enrique Montenegro Marín   +5 more
doaj  

Towards Consistency Management for a Business-Driven Development of SOA [PDF]

, 2013
The usage of the Service Oriented Architecture (SOA) along with the Business Process Management has emerged as a valuable solution for the complex (business process driven) system engineering.
Karim Dahman, Franc¸ois Charoy, Claude Godart
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source