Results 91 to 100 of about 775,103 (306)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Model-driven performance evaluation for service engineering [PDF]

open access: yes, 2007
Service engineering and service-oriented architecture as an integration and platform technology is a recent approach to software systems integration.
Boskovic, Marko   +2 more
core  

EGRESS: A Methodology for Eliciting Goals for Requirements Engineering of Secure Systems

open access: yesIEEE Open Journal of Systems Engineering
Currently, the systems engineering body of knowledge does not appropriately address secure system design considerations prior to a preliminary architecture being available for the system under design.
Martin Span, Gabe Salinger, Jeremy Daily
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Model-based engineering in real-time embedded systems: specifying timing constraints [PDF]

open access: yes, 2014
This paper presents the results from a research project on development of Real-Time Embedded Systems (RTESs) using a Model-Based Engineering (MBE) approach.
Temelkovski, D., Beus-Dukic, L.
core  

Model-Based Systems Engineering Maturity Models—A Systematic Mapping Study

open access: yesIEEE Open Journal of Systems Engineering
Model-based systems engineering (MBSE), as a logical progression from document-based systems engineering (SE), presents challenges for organizations in terms of both implementation and application.
Henriette Hofermann   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

A MODEL-BASED SYSTEMS ENGINEERING STUDY OF AIRSHIPS FOR ANTI-SUBMARINE WARFARE [PDF]

open access: yes
To support improved capability in Anti-Submarine Warfare (ASW) defense of the U.S. west coast, this research project investigates the technical and cost feasibility of developing an ASW airship.
Cromwell, Brittney L.   +3 more
core  

Assessing the State-of-Practice of Model-Based Engineering in the Embedded Systems Domain [PDF]

open access: yes, 2014
Model-Based Engineering (MBE) aims at increasing the effectiveness of engineering by using models as key artifacts in the development process. While empirical studies on the use and the effects of MBE in industry exist, there is only little work ...
Leitner, A.   +17 more
core   +1 more source

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