Results 101 to 110 of about 1,743,272 (302)
Principles for aerospace manufacturing engineering in integrated new product introduction [PDF]
, 2013 This article investigates the value-adding practices of Manufacturing Engineering for integrated New Product Introduction. A model representing how current practices align to support lean integration in Manufacturing Engineering has been defined.
Beadle, Chris +3 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Formality, Evolution, and Model-driven Software Engineering
Electronic Notes in Theoretical Computer Science, 2005 AbstractThis paper introduces an approach to software development in which a series of working implemen- tations are generated automatically from a series of formal specifications. The implementations are data stores, communicating through standard protocols.
Davies, J +4 more
openaire +3 more sources
Combining Model-Driven Engineering and Cloud Computing [PDF]
, 2010 Service-orientation and model-driven engineering are two of the most dominant software engineering paradigms nowadays. This position paper explores the synergies between them and show how they can benefit from each other.
Bruneliere, Hugo +2 more
core +1 more source
A quality management based on the Quality Model life cycle [PDF]
, 2012 Managing quality is a hard and expensive task that involves the execution and control of processes and techniques. For a good quality management, it is important to know the current state and the objective to be achieved.
Domínguez Mayo, Francisco José +4 more
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
A formal foundation for transformations in model driven engineering
Journal of Computer Science and Technology, 2008 In the MDE (Model Driven Engineering) paradigm, models are thought to be the primary conductors in all software development aspects. A PIM (Platform Independent Model) is transformed into one or more PSMs (Platform Specific Model); hence, a specific PSM ...
Roxana Silvia Giandini
doaj
An Experiment in Model Driven Architecture for e-Enterprise Systems [PDF]
, 2002 OMG's Model Driven Architecture demonstrates how a system's specification model can be used within the process of creating supporting software implementations.
Kent, Stuart, Smith, Robert P.
core
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source