Results 81 to 90 of about 23,200,592 (308)

Harnessing dynamic capabilities for data-driven business model innovation in incumbents

open access: yesDigital Business
Data-driven business model innovation (DDBMI) leverages digital technologies to seize opportunities and address challenges, yet incumbents often struggle due to their reliance on existing capabilities.
Shailesh Tripathi   +3 more
doaj   +1 more source

Fluoride ion and total dissolved solid distribution in Ethiopian Rift valley: The case of Hawassa city aquifer

open access: yesJournal of Hydrology: Regional Studies, 2018
Study region: The Main Ethiopian Rift valley (MER) region, where millions rely on fluoride contaminated drinking water that is by far higher than the WHO standard resulting skeletal and tooth decay.
Shemsu Gulta Abdurahman, Moltot Zewdie
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Sub-series 2: Publications

open access: yes, 2004
Bimonthly magazine discussing topics related to aviation and model airplane engines including collecting, restoring, maintaining, and identifying engines, along with ...
The Model Museum, Dannels, Timothy J.
core   +1 more source

Exploring Experiences with "321" Model Management for High-Risk Pregnancy: A Qualitative Study. [PDF]

open access: yesMatern Fetal Med, 2023
Sun W   +7 more
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Online Investor Sentiment via Machine Learning

open access: yesMathematics
In this paper, we propose utilizing machine learning methods to determine the expected aggregated stock market risk premium based on online investor sentiment and employing the multifold forward-validation method to select the relevant hyperparameters ...
Zongwu Cai, Pixiong Chen
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

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