Results 21 to 30 of about 957,044 (346)
New opportunities at the wild frontier
eLife, 2015 A better understanding of the natural history of model organisms will increase their value as model systems and also keep them at the forefront of research.
Jane Alfred, Ian T Baldwin
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The organism: reality or fiction? [PDF]
, 2014 What is an ‘organism’? A state of matter, or a particular type of living being chosen as an experimental object, like the fruit fly or the roundworm c. elegans, which are ‘model organisms’?
Wolfe, Charles
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Experimental Models to Study Podocyte Biology: Stock-Taking the Toolbox of Glomerular Research
Frontiers in Pediatrics, 2018 Diseases affecting the glomeruli of the kidney, the renal filtration units, are a leading cause of chronic kidney disease and end-stage renal failure. Despite recent advances in the understanding of glomerular biology, treatment of these disorders has ...
Henning Hagmann, Paul T. Brinkkoetter
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Genomic Transformation of the Picoeukaryote Ostreococcus tauri [PDF]
, 2012 Common problems hindering rapid progress in Plant Sciences include cellular, tissue and whole organism complexity, and notably the high level of genomic redundancy affecting simple genetics in higher plants. The novel model organism Ostreococcus tauri is
Bouget, François-Yves +4 more
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Human CLPP reverts the longevity phenotype of a fungal ClpP deletion strain [PDF]
, 2013 Mitochondrial maintenance crucially depends on the quality control of proteins by various chaperones, proteases and repair enzymes. While most of the involved components have been studied in some detail, little is known on the biological role of the ...
Fischer, Fabian +3 more
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Unconventional Myosins from Caenorhabditis elegans as a Probe to Study Human Orthologues
Biomolecules, 2022 Unconventional myosins are a superfamily of actin-based motor proteins that perform a number of roles in fundamental cellular processes, including (but not limited to) intracellular trafficking, cell motility, endocytosis, exocytosis and cytokinesis.
Chloe A Johnson +2 more
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Digital dissection of the model organism Xenopus laevis using contrast-enhanced computed tomography [PDF]
, 2017 The African clawed frog, Xenopus laevis, is one of the most widely used model organisms in biological research. However, the most recent anatomical description of X. laevis was produced nearly a century ago.
Ahn +62 more
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Non-mammalian model organisms in epigenetic research : an overview [PDF]
, 2020 Recent advances in sequencing technology and genome editing tools had an indisputably enormous impact on our understanding of complex biological pathways and their genetic and epigenetic regulation.
Baruah, Sri Kartik +3 more
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Veterinary Sciences, 2017 The extracellular matrix (ECM) is a dynamic scaffold within organs and tissues that enables cell morphogenesis and provides structural support. Changes in the composition and organisation of the cardiac ECM are required for normal development. Congenital
Chris J. R. Hughes, J. Roger Jacobs
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Journal of Marine Science and Engineering, 2020 Violet sea squirts are noteworthy model organisms, because they provide insights into various physiologic processes, including cell senescence, ageing, apoptosis and allorecognition. Consequently, their culture is critical to permit experimental studies.
Chiara Gregorin +3 more
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