Results 171 to 180 of about 22,233,261 (243)

Senolytics and exercise: Dual modalities for rejuvenating muscle

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican   +4 more
wiley   +1 more source

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

open access: yesInternational Journal of Cancer, Volume 159, Issue 11, Page 2633-2652, 1 December 2026.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari   +10 more
wiley   +1 more source

On the Design of Model Predictive Setpoint Controllers for Nonholonomic Multibody Systems

open access: yesProceedings in Applied Mathematics and Mechanics, Volume 26, Issue 4, December 2026.
ABSTRACT Systems subject to constraints that are not integrable to position‐level constraints pose significant challenges for setpoint control. In particular, conventional linearization techniques may fail to yield controllable approximations, since certain directions of motion are only accessible through higher‐order interactions of the control inputs.
Mario Rosenfelder   +2 more
wiley   +1 more source

On the Design of Terminal Ingredients in Periodic Model Predictive Path‐Following

open access: yesProceedings in Applied Mathematics and Mechanics, Volume 26, Issue 4, December 2026.
ABSTRACT Establishing recursive feasibility and convergence for nonlinear model predictive path‐following control (MPPFC) is a non‐trivial task, particularly when following periodic reference paths. We propose a procedure for the design of terminal ingredients in MPPFC for constrained nonlinear systems.
Mohamed Abou‐Taleb   +3 more
wiley   +1 more source

A Cyber-Physical Digital Twin Framework for State Estimation of Dendrite-Risk Prediction and Resilient Control in Solid-State Batteries. [PDF]

open access: yesGlob Chall
Subramanian S   +8 more
europepmc   +1 more source

LPV Updates for Sequentially Linearized Moving Horizon Estimation of Nonlinear Systems

open access: yesProceedings in Applied Mathematics and Mechanics, Volume 26, Issue 4, December 2026.
ABSTRACT Moving horizon estimation (MHE) provides high‐precision state estimation for nonlinear systems, but it is often limited by the substantial computational demands of solving a nonlinear optimization problem at every sampling step. To address this issue, we develop an efficient MHE scheme based on linear parameter‐varying (LPV) formulation, where
Jiaxin Ji   +3 more
wiley   +1 more source

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