Results 61 to 70 of about 242,810 (258)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Advanced pH neutralization control using model reference adaptive control (MRAC) with MIT rule [PDF]

open access: yesChemical Industry and Chemical Engineering Quarterly
This study presents the design and implementation of a Model Reference Adaptive Controller (MRAC) using the Massachusetts Institute of Technology (MIT) rule for a pH neutralization process in a continuous reactor.
Hitit Zeynep Yilmazer
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Sensorless fault-tolerant control of five-phase IPMSMs via model reference adaptive systems

open access: yesAutomatika, 2020
The present study deals with sensorless fault-tolerant control (SFTC) of five-phase Interior Permanent Magnet Synchronous Motors (IPMSMs). First, a Proportional-Integral Model Reference Adaptive System (PI-MRAS) speed estimator is proposed.
Y. Zafari, S. Shoja-Majidabad
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Model Reference Adaptive Resilient Consensus Control for Heterogeneous Multiagent Systems

open access: yesMachines
Cooperative control of multi-agent systems (MASs) is essential in engineering applications. However, malicious attacks and uncertainties can drive MASs to failure.
Huilin Tang   +3 more
doaj   +1 more source

Singularity-free multivariable model reference adaptive control

open access: yesIEEE Transactions on Automatic Control, 1993
Summary: We propose a way to solve the problem of singularities in model reference adaptive control of linear multi-input multi-output systems using a parameter modification procedure based on the least squares covariance matrix inverse. The scheme does not require any explicit prior knowledge about the leading coefficient matrix associated with the ...
Rubén G. Moctezuma, Rogelio Lozano
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy