Results 51 to 60 of about 242,810 (258)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

A Model Reference Adaptive Control Approach to Terrain Following Flight Control System

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi
Automatic Flight Control System (AFCS) Terrain Following (TF) mode allows military aircraft to fly at a certain altitude above ground level at a low altitude. TF mode reduces the probability of aircraft detection by enemy airborne radars.
Berk İnan, İbrahim Aliskan
doaj   +1 more source

Discrete Model Reference Adaptive Control System for Automatic Profiling Machine

open access: yesJournal of Control Science and Engineering, 2012
Automatic profiling machine is a movement system that has a high degree of parameter variation and high frequency of transient process, and it requires an accurate control in time.
Peng Song, Guo-kai Xu, Xiu-chun Zhao
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Discrete-time model reference adaptive control for three-phase PWM rectifiers

open access: yes电力工程技术
Three-phase pulse width modulation (PWM) rectifiers are essential power conversion devices in AC microgrids. However, DC load disturbances in the microgrid are unknown and filter capacitor parameters are imprecise, which will directly affect the control ...
Jiayan QI, Bo HOU, Yunguang GAO
doaj   +1 more source

Research on RBF neural network model reference adaptive control system based on nonlinear U – model

open access: yesAutomatika, 2020
The overall objective of this study is to design the nonlinear U-model-based radial basis function neural network model reference adaptive control system, through research into a class of complex time-varying nonlinear plants.
Fengxia Xu, Shanshan Wang, Furong Liu
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Variable Reference Model for Model Reference Adaptive Control System

open access: yesIFAC-PapersOnLine, 2015
Abstract In a conventional model reference adaptive control system, a reference model which has desired response characteristics is designed in advance. However, there is a fear that a control output cannot follow a reference model output under the model uncertainty.
T. Shiota, H. Ohmori
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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