Results 121 to 130 of about 12,063,985 (329)
Molecular Oncology, EarlyView.Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale +9 more
wiley +1 more source
Nature of Mathematical Modeling Tasks for Secondary Mathematics Preservice Teachers [PDF]
, 2017 This study investigated the nature of written modeling tasks reported by instructors of required courses in five secondary mathematics teacher education programs.
He, Jia, Jung, Hyunyi, Stehr, Eryn
core +1 more source
Protein Structure Modeling with MODELLER
, 2014 Genome sequencing projects have resulted in a rapid increase in the number of known protein sequences. In contrast, only about one-hundredth of these sequences have been characterized at atomic resolution using experimental structure determination methods.
Webb, Benjamin, Sali, Andrej
openaire +5 more sources
A guide on models and modelling
Journal of Physics: Conference Series, 2019 Abstract A new curriculum and examination programme for upper secondary school physics was recently introduced in the Netherlands. Models and modelling play an important role herein. But teachers need help in developing their PCK in this area.
P. Uylings, C.G. van Weert, Andre Heck
openaire +3 more sources
MolPROP: Molecular Property prediction with multimodal language and graph fusion
Journal of CheminformaticsPretrained deep learning models self-supervised on large datasets of language, image, and graph representations are often fine-tuned on downstream tasks and have demonstrated remarkable adaptability in a variety of applications including chatbots ...
Zachary A. Rollins +2 more
doaj +1 more source
Studies on the Cooking Mechanism of Wood. XV. Mannich Reaction on Lignin Model Compounds and the Estimation of the Amount of the Simple Guaiacyl Nucleus in Thiolignin [PDF]
, 1956 Hiroshi Mikawa +3 more
openalex +1 more source
Molecular Oncology, EarlyView.The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
A formal theory of conceptual modeling universals [PDF]
, 2004 Conceptual Modeling is a discipline of great relevance to several areas in Computer Science. In a series of papers [1,2,3] we have been using the General Ontological Language (GOL) and its underlying upper level ontology, proposed in [4,5], to evaluate ...
Guizzardi, Giancarlo +2 more
core +3 more sources