Results 91 to 100 of about 199,947 (264)
Future Wheel, unknown; but widely used and beneficial
مدیریت اطلاعات سلامت, 2015 nowadays, Health authorities are faced with different environmental, social, cultural, economical and political threats. Emerging and re-emerging diseases, changing life style, changing weather and other problems threat people’s health.
Saeed Amini, Reza Dehnavieh
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Modeling livestock ecosystem services through carbon footprint
Ecological IndicatorsRuminant livestock farming plays a significant role in climate change, as it is the economic activity that emits the most methane, along with other greenhouse gases (GHG).
Kássio R.G. Lucas, Ermias Kebreab
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
مجله اپیدمیولوژی ایران, 2019 Concurrent with globalization, some changes have been created in the performance of the universities in developed countries that have turned them into a power source for economic development.
MH Mehrolhassani +2 more
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FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Patient complaint’s profile in teaching hospitals of Isfahan
مدیریت اطلاعات سلامت, 2015 Introduction: nowadays, complaints handling is considered as a necessary part of healthcare systems for enhancing patients' satisfaction. The present study is to determine the state of the complaints handling of the visitors of Isfahan educational ...
Alireza Jabbari +4 more
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