Results 31 to 40 of about 3,102,841 (203)

Therapeutic potential of human umbilical cord mesenchymal stem cells on aortic atherosclerotic plaque in a high-fat diet rabbit model

open access: yesStem Cell Research & Therapy, 2021
Background Atherosclerosis (AS) is a complex disease caused in part by dyslipidemia and chronic inflammation. AS is associated with serious cardiovascular disease and remains the leading cause of mortality worldwide.
Yanhong Li   +8 more
doaj   +1 more source

Robot Models of Mental Disorders [PDF]

open access: yes, 2017
Alongside technological tools to support wellbeing and treatment of mental disorders, models of these disorders can also be invaluable tools to understand, support and improve these conditions.
Cañamero, Lola, Lewis, Matthew
core   +2 more sources

Generation of human induced pluripotent stem cells carrying albumin-sfGFP reporter

open access: yesStem Cell Research
Current methodologies for hepatocyte induction from human induced pluripotent stem cells (hiPSCs) have limited efficacy due to lack of a functional hepatocyte reporter.
Jinling Wang   +10 more
doaj   +1 more source

Stress and Emotion Classification Using Jitter and Shimmer Features [PDF]

open access: yes, 2007
In this paper, we evaluate the use of appended jitter and shimmer speech features for the classification of human speaking styles and of animal vocalization arousal levels.
Johnson, Michael T.   +6 more
core   +2 more sources

A novel efficient strategy to generate liver sinusoidal endothelial cells from human pluripotent stem cells

open access: yesScientific Reports
Liver sinusoidal endothelial cells (LSECs) are highly specialized endothelial cells (ECs) that play an important role in liver development and regeneration. Additionally, it is involved in various pathological processes, including steatosis, inflammation,
Shang-Ping Tian   +7 more
doaj   +1 more source

Neuroprotective effects of hypoactive Akkermansia muciniphila in MPTP-induced mouse models of Parkinson’s disease

open access: yesMicrobiology Spectrum
Parkinson’s disease (PD) has been associated with the microbiota-gut-brain axis, and probiotics have been shown to alleviate PD symptoms via various mechanisms.
Jiahui Xi   +5 more
doaj   +1 more source

Production of Highly Uniform Midbrain Organoids from Human Pluripotent Stem Cells

open access: yesStem Cells International, 2023
Brain organoids have been considered as an advanced platform for in vitro disease modeling and drug screening, but numerous roadblocks exist, such as lack of large-scale production technology and lengthy protocols with multiple manipulation steps ...
Xuerui Yao   +18 more
doaj   +1 more source

Animal models of atherosclerosis. [PDF]

open access: yes, 2017
Atherosclerosis is a significant cause of morbidity and mortality globally. Many animal models have been developed to study atherosclerosis, and permit experimental conditions, diet and environmental risk factors to be carefully controlled ...
Lee, Yee Ting   +8 more
core   +1 more source

Object-translocation induces event coding in the rat hippocampus

open access: yesCommunications Biology
Episodic memory is the ability to recall personally experienced events that are situated within specific spatial contexts. Within a navigation environment, salient objects can function as landmarks, and interactions with them can be encoded as distinct ...
Ya-Li Duan   +9 more
doaj   +1 more source

Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress

open access: yesFrontiers in Cell and Developmental Biology
Increasing evidence has demonstrated that oxidative stress impairs oocyte maturation and embryonic development. Conventionally, antioxidants have been applied in vitro systems to improve oocyte maturation and blastocyst rates.
Na Wang   +8 more
doaj   +1 more source

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