Results 61 to 70 of about 26,772,730 (350)
Rabbit models of heart disease. [PDF]
, 2008 Human heart disease is a major cause of death and disability. A variety of animal models of cardiac disease have been developed to better understand the etiology, cellular and molecular mechanisms of cardiac dysfunction and novel therapeutic strategies ...
Bers, Donald M, Pogwizd, Steven M
core
Steady-state energy balance in animal models of obesity and weight loss [PDF]
, 2016 Supported by European Union Seventh Framework Programme (FP7/2007-2013, n°266408 (Full4Health)), the Joint Programme of the Medical Faculty of Norwegian University of Science and Technology (NTNU) and St. Olav’s University Hospital, the Liaison Committee
Barrett, Perry +7 more
core +2 more sources
Development of a protocol for maintaining viability while shipping organoid-derived retinal tissue. [PDF]
, 2020 Retinal organoid technology enables generation of an inexhaustible supply of three-dimensional retinal tissue from human pluripotent stem cells (hPSCs) for regenerative medicine applications.
Binette, Francois +6 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser +6 more
wiley +1 more source
Behavioral and cognitive animal models in headache research
The Journal of Headache and Pain, 2019 Animal models have provided a growing body of information about the pathophysiology of headaches and novel therapeutic targets. In recent years, experiments in awake animals have gained attention as more relevant headache models.
D. Vurallı +3 more
semanticscholar +1 more source
Animal Models of Atherosclerosis [PDF]
, 2012 Cardiovascular disease is currently the predominant cause of mortality worldwide and its incidence is expected to increase significantly during the next decades owing to the unhealthy effects of modern lifestyle habits (e.g., obesity and lack of physical exercise). Cardiovascular death is frequently associated with acute myocardial infarction or stroke,
Fuster, Jose J. +4 more
openaire +3 more sources
Liver developmental microenvironment promotes iHSC generation from human iPSCs
Scientific ReportsHepatic stellate cells (HSCs) are liver-specific mesenchymal cells that play a crucial role in liver formation and regeneration, as well as in different pathological diseases.
Di Ye +6 more
doaj +1 more source
Insulin receptor isoform B is required for efficient proinsulin processing in pancreatic β cells
iScienceSummary: The insulin receptor (INSR, IR) has two isoforms, IRA and IRB, through alternative splicing. However, their distinct functions in vivo remain unclear. Here we generated β cell-specific IRB knockout (KO) mice (βIRBKO).
Mingchao Jiang +11 more
doaj +1 more source
iScience, 2019 Summary: Growth hormone (GH) binds to its receptor (growth hormone receptor [GHR]) to exert its pleiotropic effects on growth and metabolism. Disrupted GH/GHR actions not only fail growth but also are involved in many metabolic disorders, as shown in ...
Liyuan Ran +20 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Psychological safety (PS) is essential for teamwork, communication, and patient safety in complex healthcare environments. In pediatric oncology, interprofessional collaboration occurs under high emotional and organizational demands. Low PS may increase stress, burnout, and adverse events.
Alexandros Rahn +4 more
wiley +1 more source