Results 1 to 10 of about 10,674,828 (317)

Impact of Dose Calculation Algorithms and Radiobiological Parameters on Prediction of Cardiopulmonary Complications in Left Breast Radiation Therapy [PDF]

Journal of Biomedical Physics and Engineering
Background: Breast cancer requires evaluating treatment plans using dosimetric and biological parameters. Considering radiation dose distribution and tissue response, healthcare professionals can optimize treatment plans for better outcomes.
Niloofar Kargar, Ahad Zeinali, Mikaeil Molazadeh   +2 more
doaj   +1 more source

Robust Modelling of Biological Neuroregulators [PDF]

2005 IEEE Engineering in Medicine and Biology 27th Annual Conference, 2005
The modelling of biological neuroregulated systems is usually complex because of their non-structured and distributed architecture. Software agents are a very useful tool to use in the modelling of this kind of systems, allowing increasing the model with characteristics which are not present in the biological equivalent. This work proposes a model of a
D.R. Fernandez, J.M.G. Chamizo, F.M. Perez, A.S. Paya, F.M. Perez, A.S. Paya   +5 more
openaire   +4 more sources

Modeling Growth in Biological Materials [PDF]

SIAM Review, 2012
The biomechanical modeling of growing tissues has recently become an area of intense interest. In particular, the interplay between growth patterns and mechanical stress is of great importance, with possible applications to arterial mechanics, embryo morphogenesis, tumor development, and bone remodeling.
Gareth Wyn Jones, S. Jonathan Chapman
openaire   +3 more sources

Dietary DHA during development affects depression-like behaviors and biomarkers that emerge after puberty in adolescent rats

Journal of Lipid Research, 2015
DHA is an important omega-3 PUFA that confers neurodevelopmental benefits. Sufficient omega-3 PUFA intake has been associated with improved mood-associated measures in adult humans and rodents, but it is unknown whether DHA specifically influences these ...
Michael J. Weiser, Kelly Wynalda, Norman Salem, Jr., Christopher M. Butt   +3 more
doaj   +1 more source

CYANIDIN-3-GLUCOSIDE PROMOTES LONGEVITYAND TOLERANCE AGAINST UVA AND OXIDATIVE STRESS IN CAENORHABDITIS ELEGANS [PDF]

Exploratory Animal and Medical Research, 2023
Crude anthocyanins extracted from different fruits and vegetables extend the lifespan of various organisms. However, the effects of pure anthocyanin compounds on the lifespan are still unknown.
John Sylvester B. Nas, Paul Mark B. Medina   +1 more
doaj   +1 more source

Caffeine reduces deficits in mechanosensation and locomotion induced by L-DOPA and protects dopaminergic neurons in a transgenic Caenorhabditis elegans model of Parkinson’s disease

Pharmaceutical Biology, 2020
Context L-DOPA is the first-line drug for Parkinson’s disease (PD). However, chronic use can lead to dyskinesia. Caffeine, which is a known neuroprotectant, can potentially act as an adjunct to minimise adverse effects of L-DOPA.
Rafael Vincent M. Manalo, Paul Mark B. Medina   +1 more
doaj   +1 more source

New Prenylated Indole Homodimeric and Pteridine Alkaloids from the Marine-Derived Fungus Aspergillus austroafricanus Y32-2

Marine Drugs, 2021
Chemical investigation of secondary metabolites from the marine-derived fungus Aspergillus austroafricanus Y32-2 resulted in the isolation of two new prenylated indole alkaloid homodimers, di-6-hydroxydeoxybrevianamide E (1) and dinotoamide J (2), one ...
Peihai Li, Mengqi Zhang, Haonan Li, Rongchun Wang, Hairong Hou, Xiaobin Li, Kechun Liu, Hao Chen   +7 more
doaj   +1 more source

The Effect of a Unique Region of Parvovirus B19 Capsid Protein VP1 on Endothelial Cells

Biomolecules, 2021
Parvovirus B19 (B19V) is a widespread human pathogen possessing a high tropism for erythroid precursor cells. However, the persistence or active replication of B19V in endothelial cells (EC) has been detected in diverse human pathologies.
Ieva Rinkūnaitė, Egidijus Šimoliūnas, Daiva Bironaitė, Rasa Rutkienė, Virginija Bukelskienė, Rolandas Meškys, Julius Bogomolovas   +6 more
doaj   +1 more source

Involvement of Nrf2-HO-1/JNK-Erk Signaling Pathways in Aconitine-Induced Developmental Toxicity, Oxidative Stress, and ROS-Mitochondrial Apoptosis in Zebrafish Embryos

Frontiers in Pharmacology, 2021
Aconitine (AC), one of the bioactive diterpenoid alkaloids extracted from Aconitum plants, is widely used in traditional herbal medicine to treat various diseases.
Qing Xia, Qing Xia, Qing Xia, Shuo Gao, Shuo Gao, Samuel Rajendran Rapael Gnanamuthu, Samuel Rajendran Rapael Gnanamuthu, Samuel Rajendran Rapael Gnanamuthu, Kaiyan Zhuang, Kaiyan Zhuang, Kaiyan Zhuang, Zhenzhen Song, Zhenzhen Song, Zhenzhen Song, Yun Zhang, Yun Zhang, Yun Zhang, Xue Wang, Xue Wang, Xue Wang, Pengfei Tu, Pengfei Tu, Pengfei Tu, Jianheng Li, Kechun Liu, Kechun Liu, Kechun Liu   +26 more
doaj   +1 more source

Modelling Coordination in Biological Systems [PDF]

, 2006
We present an application of the Reo coordination paradigm to provide a compositional formal model for describing and reasoning about the behaviour of biological systems, such as regulatory gene networks. Reo governs the interaction and flow of data between components by allowing the construction of connector circuits which have a precise formal ...
D.G. Clarke (David), D. Costa (David), F. Arbab (Farhad)   +2 more
openaire   +3 more sources