Results 21 to 30 of about 26,501,681 (348)

Impact of Dose Calculation Algorithms and Radiobiological Parameters on Prediction of Cardiopulmonary Complications in Left Breast Radiation Therapy [PDF]

Journal of Biomedical Physics and Engineering
Background: Breast cancer requires evaluating treatment plans using dosimetric and biological parameters. Considering radiation dose distribution and tissue response, healthcare professionals can optimize treatment plans for better outcomes.
Niloofar Kargar, Ahad Zeinali, Mikaeil Molazadeh   +2 more
doaj   +1 more source

Involvement of Nrf2-HO-1/JNK-Erk Signaling Pathways in Aconitine-Induced Developmental Toxicity, Oxidative Stress, and ROS-Mitochondrial Apoptosis in Zebrafish Embryos

Frontiers in Pharmacology, 2021
Aconitine (AC), one of the bioactive diterpenoid alkaloids extracted from Aconitum plants, is widely used in traditional herbal medicine to treat various diseases.
Qing Xia, Qing Xia, Qing Xia, Shuo Gao, Shuo Gao, Samuel Rajendran Rapael Gnanamuthu, Samuel Rajendran Rapael Gnanamuthu, Samuel Rajendran Rapael Gnanamuthu, Kaiyan Zhuang, Kaiyan Zhuang, Kaiyan Zhuang, Zhenzhen Song, Zhenzhen Song, Zhenzhen Song, Yun Zhang, Yun Zhang, Yun Zhang, Xue Wang, Xue Wang, Xue Wang, Pengfei Tu, Pengfei Tu, Pengfei Tu, Jianheng Li, Kechun Liu, Kechun Liu, Kechun Liu   +26 more
doaj   +1 more source

Caffeine reduces deficits in mechanosensation and locomotion induced by L-DOPA and protects dopaminergic neurons in a transgenic Caenorhabditis elegans model of Parkinson’s disease

Pharmaceutical Biology, 2020
Context L-DOPA is the first-line drug for Parkinson’s disease (PD). However, chronic use can lead to dyskinesia. Caffeine, which is a known neuroprotectant, can potentially act as an adjunct to minimise adverse effects of L-DOPA.
Rafael Vincent M. Manalo, Paul Mark B. Medina   +1 more
doaj   +1 more source

Reaction-diffusion models for biological pattern formation [PDF]

, 2001
We consider the use of reaction-diffusion equations to model biological pattern formation and describe the derivation of the reaction-terms for several illustrative examples.
Crampin, E. J., Maini, P. K.
core   +1 more source

At the Biological Modeling and Simulation Frontier [PDF]

Pharmaceutical Research, 2009
We provide a rationale for and describe examples of synthetic modeling and simulation (M&S) of biological systems. We explain how synthetic methods are distinct from familiar inductive methods. Synthetic M&S is a means to better understand the mechanisms that generate normal and disease-related phenomena observed in research, and how compounds of ...
C. Anthony Hunt, C. Anthony Hunt, Sean H. J. Kim, Glen E. P. Ropella, Jesse A. Engelberg, Jonathan Tang, Shahab Sheikh-Bahaei, Tai Ning Lam   +7 more
openaire   +4 more sources

Melanins: Skin Pigments and Much More—Types, Structural Models, Biological Functions, and Formation Routes

, 2014
This review presents a general view of all types of melanin in all types of organisms. Melanin is frequently considered just an animal cutaneous pigment and is treated separately from similar fungal or bacterial pigments.
F. Solano
semanticscholar   +1 more source

Discriminative topological features reveal biological network mechanisms [PDF]

BMC Bioinformatics, 2004
BackgroundRecent genomic and bioinformatic advances have motivated the development of numerous network models intending to describe graphs of biological, technological, and sociological origin.
Manuel Middendorf, Etay Ziv, Carter Adams, Jen Hom, Robin Koytcheff, Chaya Levovitz, Gregory Woods, Linda Chen, Chris Wiggins   +8 more
semanticscholar   +1 more source

Automatic landmarking for building biological shape models [PDF]

, 2002
We present a new method for automatic landmark extraction from the contours of biological specimens. Our ultimate goal is to enable automatic identification of biological specimens in photographs and drawings held in a database.
Bayer, M.M., Hicks, Y., Manning, D.G., Marshall, D., Martin, R.R., Rosin, P.L.   +5 more
core   +3 more sources

DCIR suppresses osteoclastic proliferation and resorption by downregulating M-CSF and RANKL signaling

Frontiers in Immunology, 2023
Dendritic cell immunoreceptor (DCIR) is an inhibitory C-type lectin receptor that acts as a negative regulator in the immune system and bone metabolism.
Tomonori Kaifu, Takumi Maruhashi, Soo-Hyun Chung, Kenji Shimizu, Akira Nakamura, Yoichiro Iwakura   +5 more
doaj   +1 more source

Of (Biological) Models and Simulations [PDF]

MOJ Proteomics & Bioinformatics, 2016
Modeling and simulation are recognized as important aspects of the scientific method for more than 70 years but its adoption in biology has been slow. Debates on its representativeness, usefulness, and whether the effort spent on such endeavors is worthwhile, exist to this day.
openaire   +2 more sources