Results 21 to 30 of about 27,460,944 (326)

Melanins: Skin Pigments and Much More—Types, Structural Models, Biological Functions, and Formation Routes

open access: yes, 2014
This review presents a general view of all types of melanin in all types of organisms. Melanin is frequently considered just an animal cutaneous pigment and is treated separately from similar fungal or bacterial pigments.
F. Solano
semanticscholar   +1 more source

Biological applications of knowledge graph embedding models

open access: yesBriefings Bioinform., 2020
Complex biological systems are traditionally modelled as graphs of interconnected biological entities. These graphs, i.e. biological knowledge graphs, are then processed using graph exploratory approaches to perform different types of analytical and ...
Sameh K. Mohamed, A. Nounu, V. Nováček
semanticscholar   +1 more source

Autocatalytic Models for the Origin of Biological Homochirality. [PDF]

open access: yesChemical Reviews, 2019
Autocatalytic models for the emergence of homochirality have been of interest for more than half a century. The sole experimental example of such an amplifying autocatalytic reaction is the Soai reaction.
D. Blackmond
semanticscholar   +1 more source

Dietary DHA during development affects depression-like behaviors and biomarkers that emerge after puberty in adolescent rats

open access: yesJournal of Lipid Research, 2015
DHA is an important omega-3 PUFA that confers neurodevelopmental benefits. Sufficient omega-3 PUFA intake has been associated with improved mood-associated measures in adult humans and rodents, but it is unknown whether DHA specifically influences these ...
Michael J. Weiser   +3 more
doaj   +1 more source

New Prenylated Indole Homodimeric and Pteridine Alkaloids from the Marine-Derived Fungus Aspergillus austroafricanus Y32-2

open access: yesMarine Drugs, 2021
Chemical investigation of secondary metabolites from the marine-derived fungus Aspergillus austroafricanus Y32-2 resulted in the isolation of two new prenylated indole alkaloid homodimers, di-6-hydroxydeoxybrevianamide E (1) and dinotoamide J (2), one ...
Peihai Li   +7 more
doaj   +1 more source

Automatic landmarking for building biological shape models [PDF]

open access: yes, 2002
We present a new method for automatic landmark extraction from the contours of biological specimens. Our ultimate goal is to enable automatic identification of biological specimens in photographs and drawings held in a database.
Bayer, M.M.   +5 more
core   +3 more sources

Caffeine reduces deficits in mechanosensation and locomotion induced by L-DOPA and protects dopaminergic neurons in a transgenic Caenorhabditis elegans model of Parkinson’s disease

open access: yesPharmaceutical Biology, 2020
Context L-DOPA is the first-line drug for Parkinson’s disease (PD). However, chronic use can lead to dyskinesia. Caffeine, which is a known neuroprotectant, can potentially act as an adjunct to minimise adverse effects of L-DOPA.
Rafael Vincent M. Manalo   +1 more
doaj   +1 more source

Development and validation of computational models of cellular interaction [PDF]

open access: yes, 2004
In this paper we take the view that computational models of biological systems should satisfy two conditions – they should be able to predict function at a systems biology level, and robust techniques of validation against biological models must be ...
Holcombe, W.M.L.   +2 more
core   +1 more source

The Effect of a Unique Region of Parvovirus B19 Capsid Protein VP1 on Endothelial Cells

open access: yesBiomolecules, 2021
Parvovirus B19 (B19V) is a widespread human pathogen possessing a high tropism for erythroid precursor cells. However, the persistence or active replication of B19V in endothelial cells (EC) has been detected in diverse human pathologies.
Ieva Rinkūnaitė   +6 more
doaj   +1 more source

Involvement of Nrf2-HO-1/JNK-Erk Signaling Pathways in Aconitine-Induced Developmental Toxicity, Oxidative Stress, and ROS-Mitochondrial Apoptosis in Zebrafish Embryos

open access: yesFrontiers in Pharmacology, 2021
Aconitine (AC), one of the bioactive diterpenoid alkaloids extracted from Aconitum plants, is widely used in traditional herbal medicine to treat various diseases.
Qing Xia   +26 more
doaj   +1 more source

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