Results 21 to 30 of about 30,009,286 (350)

CYANIDIN-3-GLUCOSIDE PROMOTES LONGEVITYAND TOLERANCE AGAINST UVA AND OXIDATIVE STRESS IN CAENORHABDITIS ELEGANS [PDF]

open access: yesExploratory Animal and Medical Research, 2023
Crude anthocyanins extracted from different fruits and vegetables extend the lifespan of various organisms. However, the effects of pure anthocyanin compounds on the lifespan are still unknown.
John Sylvester B. Nas   +1 more
doaj   +1 more source

Development and validation of computational models of cellular interaction [PDF]

open access: yes, 2004
In this paper we take the view that computational models of biological systems should satisfy two conditions – they should be able to predict function at a systems biology level, and robust techniques of validation against biological models must be ...
Holcombe, W.M.L.   +2 more
core   +1 more source

Dietary DHA during development affects depression-like behaviors and biomarkers that emerge after puberty in adolescent rats

open access: yesJournal of Lipid Research, 2015
DHA is an important omega-3 PUFA that confers neurodevelopmental benefits. Sufficient omega-3 PUFA intake has been associated with improved mood-associated measures in adult humans and rodents, but it is unknown whether DHA specifically influences these ...
Michael J. Weiser   +3 more
doaj   +1 more source

Setting Parameters for Biological Models With ANIMO [PDF]

open access: yes, 2014
ANIMO (Analysis of Networks with Interactive MOdeling) is a software for modeling biological networks, such as e.g. signaling, metabolic or gene networks. An ANIMO model is essentially the sum of a network topology and a number of interaction parameters.
Karperien, Marcel   +5 more
core   +3 more sources

Melanins: Skin Pigments and Much More—Types, Structural Models, Biological Functions, and Formation Routes

open access: yes, 2014
This review presents a general view of all types of melanin in all types of organisms. Melanin is frequently considered just an animal cutaneous pigment and is treated separately from similar fungal or bacterial pigments.
F. Solano
semanticscholar   +1 more source

Caffeine reduces deficits in mechanosensation and locomotion induced by L-DOPA and protects dopaminergic neurons in a transgenic Caenorhabditis elegans model of Parkinson’s disease

open access: yesPharmaceutical Biology, 2020
Context L-DOPA is the first-line drug for Parkinson’s disease (PD). However, chronic use can lead to dyskinesia. Caffeine, which is a known neuroprotectant, can potentially act as an adjunct to minimise adverse effects of L-DOPA.
Rafael Vincent M. Manalo   +1 more
doaj   +1 more source

New Prenylated Indole Homodimeric and Pteridine Alkaloids from the Marine-Derived Fungus Aspergillus austroafricanus Y32-2

open access: yesMarine Drugs, 2021
Chemical investigation of secondary metabolites from the marine-derived fungus Aspergillus austroafricanus Y32-2 resulted in the isolation of two new prenylated indole alkaloid homodimers, di-6-hydroxydeoxybrevianamide E (1) and dinotoamide J (2), one ...
Peihai Li   +7 more
doaj   +1 more source

The Effect of a Unique Region of Parvovirus B19 Capsid Protein VP1 on Endothelial Cells

open access: yesBiomolecules, 2021
Parvovirus B19 (B19V) is a widespread human pathogen possessing a high tropism for erythroid precursor cells. However, the persistence or active replication of B19V in endothelial cells (EC) has been detected in diverse human pathologies.
Ieva Rinkūnaitė   +6 more
doaj   +1 more source

Discriminative topological features reveal biological network mechanisms [PDF]

open access: yesBMC Bioinformatics, 2004
BackgroundRecent genomic and bioinformatic advances have motivated the development of numerous network models intending to describe graphs of biological, technological, and sociological origin.
Manuel Middendorf   +8 more
semanticscholar   +1 more source

Dynamic Influence Networks for Rule-based Models [PDF]

open access: yes, 2017
We introduce the Dynamic Influence Network (DIN), a novel visual analytics technique for representing and analyzing rule-based models of protein-protein interaction networks.
Boutillier, Pierre   +6 more
core   +5 more sources

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