Results 11 to 20 of about 812,277 (267)

Structural modelling of the cardiovascular system [PDF]

Biomechanics and Modeling in Mechanobiology, 2018
Computational modelling of the cardiovascular system offers much promise, but represents a truly interdisciplinary challenge, requiring knowledge of physiology, mechanics of materials, fluid dynamics and biochemistry. This paper aims to provide a summary of the recent advances in cardiovascular structural modelling, including the numerical methods ...
Benjamin Owen, Nicholas Bojdo, Andrey Jivkov, Bernard Keavney, Alistair Revell   +4 more
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Roadmap for cardiovascular circulation model [PDF]

The Journal of Physiology, 2016
AbstractComputational models of many aspects of the mammalian cardiovascular circulation have been developed. Indeed, along with orthopaedics, this area of physiology is one that has attracted much interest from engineers, presumably because the equations governing blood flow in the vascular system are well understood and can be solved with well ...
Soroush Safaei, Christopher P. Bradley, Vinod Suresh, Kumar Mithraratne, Alexandre Muller, Harvey Ho, David Ladd, Leif R. Hellevik, Stig W. Omholt, J. Geoffrey Chase, Lucas O. Müller, Sansuke M. Watanabe, Pablo J. Blanco, Bernard de Bono, Peter J. Hunter   +14 more
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Data for cardiovascular modeling

Journal of the American College of Cardiology, 1989
Data are required for a meaningful approach to quality and cost-conscious cardiovascular care. How to identify the types of data available and their sources, advantages and limitations to their use, issues involved in combining data from different sources for decision modeling and some possible solutions are discussed in this summary of the Working ...
Muhlbaier, Lawrence H., Pryor, David B.
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Modelling the cardiovascular system

Critical Care and Resuscitation, 2007
Cardiovascular disease claims more lives than any other disease in westernised countries, affecting millions. Pinpointing cardiovascular system dysfunction is often difficult because the clinical signs, or the availability and interpretation of physiological measurements, are unreliable. Often patient-specific information is incomplete or confusing, as
Shaw, G. M., Chase, J. G., Starfinger, C., Smith, B., Hann, C. E., Desaive, Thomas, Ghuysen, Alexandre   +6 more
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A Novel Nonsense MMP21 Variant Causes Dextrocardia and Congenital Heart Disease in a Han Chinese Patient

Frontiers in Cardiovascular Medicine, 2020
The position and morphology of human internal organs are asymmetrically distributed along the left–right axis. Aberrant left–right patterning in the developing embryo can lead to a series of congenital laterality defects, such as dextrocardia and ...
Zhuang-Zhuang Yuan, Zhuang-Zhuang Yuan, Zhuang-Zhuang Yuan, Liang-Liang Fan, Liang-Liang Fan, Zi-Chen Jiang, Yi-Feng Yang, Zhi-Ping Tan   +7 more
doaj   +1 more source

Refining murine heterotopic heart transplantation: A model to study ischemia and reperfusion injury in donation after circulatory death hearts

Animal Models and Experimental Medicine, 2021
Heart transplantation is a lifesaving procedure, which is limited by the availability of donor hearts. Using hearts from donors after circulatory death, which have sustained global ischemia, requires thorough studies on reliable and reproducible models ...
Mohammed Quader, Renee Cholyway, Niluka Wickramaratne, Oluwatoyin Akande, Martin Mangino, Eleonora Mezzaroma, Adolfo G. Mauro, Qun Chen, Alexander Kantlis, Stefano Toldo   +9 more
doaj   +1 more source

Function and distribution of circulating human PCSK9 expressed extrahepatically in transgenic mice

Journal of Lipid Research, 2009
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is predominantly expressed in liver and regulates cholesterol metabolism by down regulating liver LDL receptor (LDLR) proteins.
Yi Luo, Laurie Warren, Donghui Xia, Heather Jensen, Thomas Sand, Stephen Petras, Wenning Qin, Kenneth S. Miller, Julie Hawkins   +8 more
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Plasma lipidomic signatures of spontaneous obese rhesus monkeys

Lipids in Health and Disease, 2019
Background Obesity plays crucial roles in the pathogenesis of metabolic diseases such as hyperlipidemia, nonalcoholic fatty liver disease (NAFLD), and type 2 diabetes (T2D).
Junlong Wang, Linqiang Zhang, Ruyue Xiao, Yunhai Li, Shasha Liao, Zhiguo Zhang, Wenhui Yang, Bin Liang   +7 more
doaj   +1 more source

Animal Models of Cardiovascular Diseases [PDF]

BioMed Research International, 2011
Cardiovascular diseases are the first leading cause of death and morbidity in developed countries. The use of animal models have contributed to increase our knowledge, providing new approaches focused to improve the diagnostic and the treatment of these pathologies.
Zaragoza, Carlos, Gomez-Guerrero, Carmen, Martin-Ventura, Jose Luis, Blanco-Colio, Luis, Lavín Plaza, Begoña, Mallavia, Beñat, Tarin, Carlos, Mas, Sebastian, Ortiz, Alberto, Egido, Jesus   +9 more
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Zebrafish models of cardiovascular disease

Heart Failure Reviews, 2016
Cardiovascular disease (CVD) is one of the leading causes of death worldwide. The most significant risk factors associated with the development of heart diseases include genetic and environmental factors such as hypertension, high blood cholesterol levels, diabetes, smoking, and obesity.
Despina Bournele, Dimitris Beis
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