Results 21 to 30 of about 2,144,277 (316)

The epigenetic modifier Fam208a is required to maintain epiblast cell fitness

Scientific Reports, 2017
Gastrulation initiates with the formation of the primitive streak, during which, cells of the epiblast delaminate to form the mesoderm and definitive endoderm.
Shohag Bhargava, Brian Cox, Christiana Polydorou, Veronika Gresakova, Vladimir Korinek, Hynek Strnad, Radislav Sedlacek, Trevor Allan Epp, Kallayanee Chawengsaksophak   +8 more
doaj   +1 more source

Molecular footprints of the Holocene retreat of dwarf birch in Britain [PDF]

, 2014
© 2014 The Authors. Molecular Ecology Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original ...
Bodles, WJA, Borrell, JS, Kuttapitiya, A, Richard A. Nichols, Wang, N, Nian Wang, William J A. Bodles, Anasuya Kuttapitiya, Richard J A. Buggs, Buggs, RJA, James S. Borrell, Nichols, RA   +11 more
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Potential Molecular Targets for Treating Neuropathic Orofacial Pain Based on Current Findings in Animal Models

, 2021
This review highlights potential molecular targets for treating neuropathic orofacial pain based on current findings in animal models. Preclinical research is currently elucidating the pathophysiology of the disease and identifying the molecular targets ...
Takahiro Kurose, Yukinori Nagakura, Shogo Nagaoka   +2 more
core   +1 more source

Chimeric Antigen Receptor T Cells Targeting Cell Surface GRP78 to Eradicate Acute Myeloid Leukemia

Frontiers in Cell and Developmental Biology, 2022
Acute myeloid leukemia (AML) is a serious, life-threatening hematological malignancy. The treatment outcome of relapsed or refractory AML patients remains dismal, and new treatment options are needed.
Wei Yu, Hang Zhang, Yuncang Yuan, Jie Tang, Xinchuan Chen, Ting Liu, Xudong Zhao   +6 more
doaj   +1 more source

Antigenic molecular mimicry in viral-mediated protection from cancer: the HIV case

Journal of Translational Medicine, 2022
Background People living with HIV/AIDS (PLWHA) show a reduced incidence for three cancer types, namely breast, prostate and colon cancers. In the present study, we assessed whether a molecular mimicry between HIV epitopes and tumor associated antigens ...
Carmen Manolio, Concetta Ragone, Beatrice Cavalluzzo, Angela Mauriello, Maria Lina Tornesello, Franco M. Buonaguro, Angelo Salomone Megna, Giovanna D’Alessio, Roberta Penta, Maria Tagliamonte, Luigi Buonaguro   +10 more
doaj   +1 more source

Cellular, molecular and functional characterisation of YAC transgenic mouse models of Friedreich Ataxia [PDF]

, 2014
Copyright © 2014 Anjomani Virmouni et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author ...
Al-Mahdawi, S, Al-Mahdawi Sahar, Anjomani Virmouni Sara, Virmouni, SA, Sandi, C, Chiranjeevi S, Pook, MA, Sahar Al-Mahdawi, Chiranjeevi Sandi, Sandi Chiranjeevi, Chiranjeevi Sandi (283956), Sara Anjomani Virmouni, Mark A. Pook (126056), Pook Mark A., Mark A. Pook, Sara Anjomani Virmouni (627000), Mark A Pook, Sahar Al-Mahdawi (126054)   +17 more
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Genetic profile and functional proteomics of anal squamous cell carcinoma: proposal for a molecular classification [PDF]

, 2020
Carcinoma anal de cèl·lules escamoses; Biologia molecular; ProteòmicaAnal squamous cell carcinoma; Molecular biology; ProteomicsCarcinoma anal de células escamosas; Biología molecular; ProteómicaAnal squamous cell carcinoma is a rare tumor.
Mendiola, Marta, G-Pastrián, Laura, Capdevila Castillon, Jaume, Ghanem, Ismael, Trilla-Fuertes, Lucía, Maurel, Joan, Gámez‑Pozo, Angelo   +6 more
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Generation and Characterization of a Novel Angelman Syndrome Mouse Model with a Full Deletion of the Ube3a Gene

Cells, 2022
Angelman syndrome (AS) is a neurodevelopmental disorder caused by deficits in maternally inherited UBE3A. The disease is characterized by intellectual disability, impaired motor skills, and behavioral deficits, including increased anxiety and autism ...
Linn Amanda Syding, Agnieszka Kubik-Zahorodna, Petr Nickl, Vendula Novosadova, Jana Kopkanova, Petr Kasparek, Jan Prochazka, Radislav Sedlacek   +7 more
doaj   +1 more source

Acceleration of Coarse Grain Molecular Dynamics on GPU Architectures [PDF]

, 2013
Coarse grain (CG) molecular models have been proposed to simulate complex sys- tems with lower computational overheads and longer timescales with respect to atom- istic level models.
Acquaviva*, Andrea, FICARRA, ELISA, ACQUAVIVA, ANDREA, Enrico Macii, Andrea Acquaviva, Elisa Ficarra, SHKURTI, ARDITA, Ardita Shkurti, Macii, Enrico, Ficarra*, Elisa, Mario Orsi, Orsi, Mario   +11 more
core   +1 more source

Coarse-grained molecular models of the surface of hair

, 2021
We present a coarse-grained molecular model of the surface of human hair, which consists of a lipid monolayer, in the MARTINI framework. Using molecular dynamics simulations, we identify a lipid grafting distance that yields a monolayer thickness ...
Steven H., Page, Peter H., Koenig, James P., Ewen, Yuri, Roiter, Erik, Weiand, Daniele , Dini, Stefano, Angioletti-Uberti   +6 more
core   +1 more source