Results 121 to 130 of about 29,999,610 (319)
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
EntropyWe investigate diffusion models generating synthetic samples from the probability distribution represented by the ground truth (GT) samples. We focus on how GT sample information is encoded in the score function (SF), computed (not simulated) from the ...
Hamidreza Behjoo, Michael Chertkov
doaj +1 more source
Statistical Inference in Calibrated Models [PDF]
Journal of Applied Econometrics, 1994 SUMMARY This paper describes a Monte Carlo procedure to assess the performance of calibrated dynamic general equilibrium models. The procedure formalizes the choice of parameters and the evaluation of the model and provides an efficient way to conduct a sensitivity analysis for perturbations of the parameters within a reasonable range.
openaire +4 more sources
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
SAMPLING IN EXTERNAL AUDIT - THE MONETARY UNIT SAMPLING METHOD
Вісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2016 This article approaches the general issue of diminishing the evidence investigation space in audit activities, by means of sampling techniques, given that in the instance of a significant data volume an exhaustive examination of the assessed popula¬tion ...
E. Dascalu, L. Nasta
doaj +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
3-D facial expression representation using statistical shape models [PDF]
, 2008 This poster describes a methodology for facial expressions representation, using 3-D/4-D data, based on the statistical shape modelling technology. The proposed method uses a shape space vector to model surface deformations, and a modified iterative ...
Ait-Boudaoud, Djamel +3 more
core
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Statistical Models of Reconstructed Phase Spaces for Signal Classification [PDF]
, 2006 This paper introduces a novel approach to the analysis and classification of time series signals using statistical models of reconstructed phase spaces.
Johnson, Michael T +4 more
core +1 more source