Results 51 to 60 of about 394,456 (275)

Predictive modeling of immune escape and antigenic grouping of SARS-CoV-2 variants

Journal of Virology
The ongoing adaptive evolution of Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is characterized by the continued emergence of variants with increased transmissibility and the ability to escape infection- and/or vaccine-induced immunity ...
Arshan Nasir, Diana Lee, Laura E. Avena, Daniela Montes Berrueta, Tessa Speidel, Kai Wu, Yadunanda Budigi, Andrea Carfi, Guillaume B. E. Stewart-Jones, Darin Edwards   +9 more
doaj   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Government as orchestrator: Ecosystem transformation at scale and speed

Strategic Management Journal, EarlyView.
Abstract Research Summary Grand challenges are ecosystem challenges: success depends on aligning a multilateral set of public and private sector actors whose interdependent contributions determine whether a mission is achieved. This study examines how government can orchestrate ecosystem alignment by leveraging distinctive capabilities to deliver ...
Ron Adner
wiley   +1 more source

UMA GEOGRAFIA MODERNA PARA UMA ESCOLA MODERNA

Caminhos de Geografia, 2012
O presente artigo pretende abordar a história da Geografia Escolar, tendo por referência as primeiras tentativas de renovação da geografia escolar. Tais tentativas representavam anseios de intelectuais no sentido de "modernizar" a disciplina escolar. Exemplos disso são os famosos pareceres de Ruy Barbosa, que de forma pioneira fez severas críticas a ...
openaire   +3 more sources

H-Moderna

, 2019
Esta é a página da H-Moderna: Rede Brasileira de Estudos em História Moderna. A H-Moderna pretende congregar os pesquisadores e pesquisadoras que, no Brasil, se dedicam ao estudo da Época Moderna.
hmoderna
core  

Advances in research on layered double hydroxides for biomedical applications

Smart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang, Zhiping Zhang, Zhao Wang, Hao Zhang, Yen Leng Pak, Yingying Jing, Yurong Guo, Fang Li, Xiao Wang, Quanxiang Han, Lei Yu, Xuejiao Li, Xing Gao, Jibin Song   +13 more
wiley   +1 more source

A review of the immunogenicity and safety of booster doses of omicron variant-containing mRNA-1273 COVID-19 vaccines in adults and children

Expert Review of Vaccines
Introduction Vaccination against SARS-CoV-2 is an integral pillar of the public health approach to COVID-19. With the emergence of variants of concern that increase transmissibility and escape from vaccine- or infection-induced protection, vaccines have ...
Frances Priddy, Spyros Chalkias, Brandon Essink, Jordan Whatley, Adam Brosz, Ivan T. Lee, Jing Feng, LaRee Tracy, Weiping Deng, Wen Zhou, Honghong Zhou, Avika Dixit, Sabine Schnyder Ghamloush, Bethany Girard, Elizabeth de Windt, Anne Yeakey, Jacqueline Miller, Rituparna Das, Barbara J. Kuter   +18 more
doaj   +1 more source

Particelle in Fisica Moderna

This paper provides a philosophical analysis of the contemporary debate surrounding the nature of particles, as described by one of the most recent quantum theories, Quantum Field Theory. Specifically, the paper will present the formal and philosophical details underlying the discussion on the ontological and epistemological status of particles.
A. Collavini, L. Gasparinetti
openaire   +3 more sources

Fronting in Old Catalan: Asymmetries between Narration and Reported Speech1

Transactions of the Philological Society, Volume 123, Issue 1, Page 1-28, March 2025.
Abstract This article explores the distribution, syntax, and information structure of XVS clauses in the narrative text and the reported speech of a thirteenth‐century Old Catalan chronicle, the Llibre dels Fets. It is shown that XVS occurs mainly within reported speech and in embedded clauses.
Afra Pujol i Campeny
wiley   +1 more source

Clinical Impact and Cost-Effectiveness of Updated 2023/24 COVID-19 mRNA Vaccination in High-Risk Populations in the United States

Infectious Diseases and Therapy
Introduction In the post-pandemic era, people with underlying medical conditions continue to be at increased risk for severe COVID-19 disease, yet COVID-19 vaccination uptake remains low.
Keya Joshi, Mariia Dronova, Ewelina Paterak, Van H. Nguyen, Hagit Kopel, James Mansi, Nicolas Van de Velde, Ekkehard Beck   +7 more
doaj   +1 more source