Results 31 to 40 of about 394,456 (275)

Immunogenicity and safety of mRNA-based seasonal influenza vaccines encoding hemagglutinin and neuraminidase

Nature Communications
Current influenza vaccines induce immune responses to hemagglutinin (HA), a surface glycoprotein of seasonal influenza viruses, but have suboptimal effectiveness. mRNA vaccines may improve protection by targeting additional antigens such as neuraminidase
Amanda K. Rudman Spergel, Ivan T. Lee, Kindra Koslovsky, Kristi Schaefers, Andrei Avanesov, Douglas K. Logan, John Hemmersmeier, David Ensz, Daniel Stadlbauer, Bo Hu, Alicia Pucci, Jignesh Vakil, Robert Paris, Jintanat Ananworanich, Raffael Nachbagauer   +14 more
doaj   +1 more source

El final de las elecciones de diputados y personeros del común en Sevilla (1803-1808) [PDF]

, 1999
Actas de la V Reunión Científica de la Asociación Española de Historia Moderna.
Campese Gallego, Fernando Javier, Campese Gallego, Fernando J.   +1 more
core   +1 more source

A scoping review of adverse events associated with concomitant beta‐adrenoreceptor blockers and selective serotonin reuptake inhibitors

British Journal of Clinical Pharmacology, EarlyView.
Beta‐adrenoreceptor blockers (beta‐blockers) and selective serotonin reuptake inhibitors (SSRIs) are commonly used medications and often used together, such as for the treatment of anxiety. However, there is no recent review of any potential adverse events related to concomitant use of medicines from each group.
Ziyi Cai, James Sutton, Charlotte Archer, Caroline S. Copeland, Joseph Hayes, Charles E. Leonard, Nicky Lidbetter, Kenneth K. C. Man, Faraz Mughal, Ian C. K. Wong, Hayley C. Gorton   +10 more
wiley   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Immune correlates analysis of mRNA-1345 RSV vaccine efficacy clinical trial

Nature Communications
Identifying an immunologic marker as a correlate of protection (CoP) for RSV vaccination is important. In the pivotal phase 3 trial, the mRNA-1345 vaccine demonstrated efficacy against RSV in older adults (NCT05127434).
Chong Ma, Jiejun Du, Lan Lan, Archana Kapoor, Gonzalo Perez Marc, Gilberto Jimenez, Christopher J. A. Duncan, Nancy Le Cam, Nina Lin, Frances Priddy, Sanjay Garg, Sonia K. Stoszek, Christine A. Shaw, Jaya Goswami, Eleanor Wilson, Rituparna Das, Honghong Zhou, Lingyi Zheng   +17 more
doaj   +1 more source

Enhancing Evidence Generation by Linking Randomized Clinical Trials to Real‐World Data: The INVESTED‐Medicare Linkage Study

Clinical Pharmacology &Therapeutics, EarlyView.
Real‐world evidence (RWE) derived from real‐world data (RWD) can complement randomized controlled trials (RCTs), yet the validity of RWD relative to RCT data remains insufficiently characterized. We obtained post hoc consent and linked individual participant data from the US‐based INVESTED trial (2016–2019) with Medicare fee‐for‐service claims (2012 ...
Hanseul Cho, HoJin Shin, Mehdi Najafzadeh, Brian Claggett, Janinne Ortega‐Montiel, Jun Liu, Julie M. Paik, Narlina F. Lalani, Marie C. Bradley, John Concato, Scott D. Solomon, Orly Vardeny, Elisabetta Patorno   +12 more
wiley   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

Instituciones sociales modernas

Revista de Fomento Social, 1954
.
openaire   +1 more source

Las colonias extranjeras en el Puerto de Santa María durante el reinado de Carlos IV [PDF]

, 1991
Actas de la I Reunión Científica de la Asociación Española de Historia Moderna, Madrid, 11 al 13 de diciembre de 1989Peer ...
Iglesias Rodríguez, Juan José
core   +1 more source

Clinical features of the postictal state in adults with epilepsy: A cross‐sectional survey

Epilepsia, EarlyView.
Abstract Objective Persons with epilepsy may experience many postictal symptoms after a seizure, which can significantly impact quality of life. We aimed to determine the frequency, duration, and severity of postictal symptoms to better characterize the postictal period.
Ann Subota, Sundus Khan, Sara Lukmanji, Jeanie Y. Y. Lee, Meng Wang, Pamela Roach, Samuel Wiebe, Paolo Federico, Jeffrey Buchhalter, G. Campbell Teskey, Shaily Singh, Colin Bruce Josephson, Nathalie Jetté   +12 more
wiley   +1 more source