Results 271 to 280 of about 600,227 (293)

Strategies for the episomal modification of cells.

Current opinion in molecular therapeutics, 2009
The clinical application of gene therapy has become a reality with the treatment of patients with X-linked SCID (SCID-X1) using a modified retrovirus. This success has been tempered by the toxicity of the vector used in this trial, which led to oncogenesis in several of the treated patients.
Suet Ping, Wong, Orestis, Argyros, Charles, Coutelle, Richard P, Harbottle   +3 more
openaire   +1 more source

Allosteric Modification of Hemoglobin by RSR13 as a Therapeutic Strategy

2003
RSR13 binds to hemoglobin (Hb), reduces oxygen (O2) binding affinity, and enhances O2 unloading from Hb to hypoxic tissue. Tissue hypoxia is common to cancer, surgery, myocardial ischemia, and stroke. RSR13 increases tumor pO2, reduces tumor hypoxic fraction and because O2 is necessary to maximize the effectiveness of radiation therapy, RSR13 enhances ...
Robert P, Steffen, Jean-Francois, Liard, Michael J, Gerber, Stephen J, Hoffman   +3 more
openaire   +2 more sources

Acoustical Theory of Vowel Modification Strategies in Belting

Journal of Voice
Various authors have argued that belting is to be produced by "speech-like" sounds, with the first and second supraglottic vocal tract resonances (fR1 and fR2) at frequencies of the vowels determined by the lyrics to be sung. Acoustically, the hallmark of belting has been identified as a dominant second harmonic, possibly enhanced by first resonance ...
Christian T. Herbst, Brad H. Story, David Meyer   +2 more
openaire   +2 more sources

Recent progress in emerging BiPO4-based photocatalysts: Synthesis, properties, modification strategies, and photocatalytic applications

Journal of Materials Science and Technology, 2022
Pankaj Raizada, Aftab Aslam Parwaz Khan, Van-Huy Nguyen   +2 more
exaly  

Recent Progress in the Emerging Modification Strategies for Layered Oxide Cathodes toward Practicable Sodium Ion Batteries

Advanced Energy Materials, 2023
Guanglin Wan, Genqiang Zhang
exaly  

Strategies for Genetic Modification of Parasites

Annals of the New York Academy of Sciences, 1989
openaire   +2 more sources

Enhanced microalgal lipid production for biofuel using different strategies including genetic modification of microalgae: A review

Progress in Energy and Combustion Science, 2023
Kuan Shiong Khoo, Kit Wayne Chew, Amit Bhatnagar   +2 more
exaly  

Data Analysis Strategies for Protein Modification Identification

2016
Mass spectrometry-based proteomics provides a powerful tool for large-scale analysis of protein modifications. Statistical and computational analysis of mass spectrometry data is a key step in protein modification identification. This chapter presents common and advanced data analysis strategies for modification identification, including variable ...
openaire   +2 more sources

A review: Modification strategies of nickel-rich layer structure cathode (Ni ≥ 0.8) materials for lithium ion power batteries

Journal of Energy Chemistry, 2021
Haijian Lv, Daobin Mu
exaly  

Modification strategies on transition metal-based electrocatalysts for efficient water splitting

Journal of Energy Chemistry, 2021
Yaotian Yan, Pengcheng Wang, Junlei Qi   +2 more
exaly