Results 31 to 40 of about 8,885,090 (257)

Envolvimento do sistema monoaminérgico no efeito antidepressivo do extrato das folhas de Schinus Molle L. em camundongos [PDF]

, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.Schinus molle L. (Anacardiaceae), among other uses, is popularly employed for the treatment of depression.
Machado, Daniele Guilhermano
core  

The Effect of Dayak Onion Extract (Eleutherine palmifolia (L.) Merr) on Swimming Time and Oxidative Stress Levels in Mice with the Forced Swimming Test Model [PDF]

, 2023
Excessive physical exercise can increase the occurrence of oxidative stress, which is characterized by cell damage caused by free radicals. Antioxidants found in Dayak Onion such as flavonoids, saponins, tannins, and vitamin C can be used as alternative ...
Listyawati, Shanti, Doewes, Muchsin, Ramadhani, Aulia   +2 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Antidepressant-Like Effect of the Polymethoxylated Flavone Tangeretin from Citrus Peels: The Role of Serotonergic Mechanisms

Psychiatry and Behavioral Sciences
Objective: Depression is a mood disorder characterized by a set of emotional, cognitive, physical and behavioral symptoms. Low response rate to antidepressant treatment in patients with depression, late onset of action, side effects due to long-term drug
Ozgur Devrim Can, Nesime İnci Guner
doaj   +1 more source

Modulação do comportamento de ratos submetidos ao teste do nado forçado pelo receptor vanilóide de potencial transitório tipo 1 do hipocampo [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaA depressão é um sério transtorno do humor que acomete grande parte da sociedade atual. O hipocampo é uma das regiões
Vanvossen, Ana Carolina
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Glycine/NMDA Receptor Pathway Mediates the Rapid-onset Antidepressant Effect of Alkaloids From Trichilia Monadelpha

Basic and Clinical Neuroscience, 2021
Introduction: Major depressive disorder is often associated with suicidal tendencies, and this condition accentuates the need for rapid-acting antidepressants.
Kennedy Kwami Edem Kukuia, Jeffrey Amoako Mensah, Patrick Amoateng, Dorcas Osei-Safo, Awo Efua Koomson, Joseph Torbi, Donatus Wewura Adongo, Elvis Ofori Ameyaw, Inemesit Okon Ben, Seth Kwabena Amponsah, Kwasi Agyei Bugyei, Isaac Julius Asiedu-Gyekye   +11 more
doaj  

Estudos da estrutura comportamental de camundongos nos testes de nado forçado e da suspensão pela cauda [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em FarmacologiaA depressão é considerada uma doença potencialmente ameaçadora à vida, com um índice de suicídio chegando a 15% entre
Costa, Ana Paula Ramos
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Agomelatine-induced changes in monoamine levels of the diabetic brain: treatment of diabetesinduced depressive behavior

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia, which is caused by failure in insulin secretion and/or action that triggers various acute and chronic complications. The central nervous system complications of
Nafiz Oncu Can, Saniye Ozcan, Murat Kozanli, Taliha Harika Aydin   +3 more
doaj