Results 21 to 30 of about 8,885,090 (257)

Studying the adaptogenic activity of a series of tetrahydropyrido[2,1-b] [1,3,5] thiadiazine derivatives

Бюллетень сибирской медицины, 2019
Introduction. In the modern world people are exposed to the influence of adverse psychological and physical factors, escalating in intensity. The search for new pharmacodynamic effects of [1,3,5]-thiadiazine derivatives designated by significant ...
E. Yu. Bibik, I. A. Nekrasa, A. V. Demenko, K. A. Frolov, V. V. Dotsenko, S. G. Krivokolysko   +5 more
doaj   +1 more source

Role of intermittent fasting on improvement of cognitive functions in rat model of type 2 diabetes [PDF]

Zagazig University Medical Journal
Background: The link between diabetes mellitus and cognitive impairment becomes evident, making it important to find means to maintain cognitive performance in diabetic patients.
Radwa Al-Sayed, Aya Mohamed, Mai Hasan, Samia Hussein, Eman Mohamed   +4 more
doaj   +1 more source

Elettaria cardamomum Effects on Sleep-Deprived Induced Chronic Fatigue in Rats [PDF]

Research Journal of Pharmacognosy
Background and objective: Fatigue is a complex condition impacting both physical and mental performance, classified into acute and chronic types. Chronic fatigue can arise from prolonged sleep deprivation, negatively affecting cognitive function and ...
Seyyed Ahmad Askari, Somayeh Esmaeili, Maliheh Soodi, Sadegh Rajabi, Homa Hajimehdipoor*   +4 more
doaj   +1 more source

Idazoxan and 8-OH-DPAT Modify the Behavioral Effects Induced by Either NA, or 5-HT, or Dual NA/5-HT Reuptake Inhibition in the Rat Forced Swimming Test [PDF]

Neuropsychopharmacology, 2001
The rat forced swimming test (FST) predicts the efficacy of antidepressants, which decrease immobility duration in the test, and can distinguish selective serotonin (5-HT) and noradrenaline (NA) reuptake inhibitors, which, respectively, increase swimming and climbing behaviors.
J P, Rénéric, M, Bouvard, L, Stinus
openaire   +2 more sources

Perbandingan efektivitas antidepresan ekstrak air rimpang acorus calamus L. antara metode forced swimming test dan metode waterwhell pada mencit betina [PDF]

, 2003
Telah dilakukan penelitian dengan membandingkan metode Waterwheel dan metode Forced Swimming Test menggunakan ekstrak air rimpang Acorus calamus, L ( kadar 80%) pada mencit putih betina dengan waktu pemberian malam hari.
Fadli, Muhammad
core   +1 more source

Involvement of adrenergic and serotonergic receptors in antidepressant-like effect of urocortin 3 in a modified forced swimming test in mice

Brain Research Bulletin, 2008
Most of the evidence suggests that peptides in the corticotropin-releasing factor (CRF) family act on CRF receptors and are involved in depressive disorders. Urocortin 3 (Ucn 3) is specific for CRF type 2 (CRF(2)) receptors and mediates anxiolytic-like action. Little is known about the roles of Ucn 3 and CRH(2) receptors on depressive disorders.
Masaru, Tanaka, Gyula, Telegdy
openaire   +2 more sources

Effect of imipramine treatment on forced swimming.

, 2013
Immobility time of Pdlim5 hetero KO and wild-type mice in the forced swimming test with saline or chronic imipramine administration.
Hiroki Ishiguro (40697), Maya Ishikawa (400588), Yasue Horiuchi (142546), Yoshimi Iijima (400590), Yoshiko Tanabe (400591), Nobuko Kaito (400589), Tadao Arinami (40713)   +6 more
core   +1 more source

Forced swimming test and mechanisms of depression [PDF]

, 2015
Depression is a severe psychical disorder belonging to affective disorders. Nowadays, it belongs to the most common psychical disorders and prevalence is between 5 % to 16 %. An animal research is essential to study mechanisms of depression.
Janďourková, Pavla
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

A standardized Orthosiphon aristatus extract improves forced-swimming performance and modulates hematological and hepatic biochemical parameters in paclitaxel-treated mice

Frontiers in Pharmacology
Cancer-related fatigue is a prevalent and debilitating condition among patients undergoing chemotherapy, markedly impairing quality of life and treatment adherence. This multifactorial syndrome arises from both the malignancy itself and treatment-related
Fouad Saleih Resq Al-Suede, Nur Fitriyani Afiqah Abu Bakar, Rapidah Mohamad, Mohd Shahrul Ridzuan Hamil, Ashwaq Hamid Salem Yehya, Chern Ein Oon, Zurina Hassan, Aman Shah Abdul Majid, Amin Malik Shah Abdul Majid, Amin Malik Shah Abdul Majid, Muhammad Asyraf Abduraman   +10 more
doaj   +1 more source