Results 11 to 20 of about 780,037 (214)

Gastro-retentive oral drug delivery systems: a promising approach for narrow absorption window drugs [PDF]

Journal of Advanced Biomedical and Pharmaceutical Sciences, 2019
Drugs with narrow absorption window (NAW) are those drugs that are absorbed from a specific region (most notably first part) of the gastrointestinal tract.
Mohamed Ibrahim, Youssef Naguib, Hatem Sarhan, Hamdy Abdelkader   +3 more
doaj   +1 more source

Comparative Study of Selected Excipients’ Influence on Carvedilol Release from Hypromellose Matrix Tablets

Pharmaceutics, 2023
Solid dosage forms based on hypromellose (HPMC) with prolonged/extended drug release are very important from the research and industrial viewpoint. In the present research, the influence of selected excipients on carvedilol release performance from HPMC ...
Tadej Ojsteršek, Grega Hudovornik, Franc Vrečer   +2 more
doaj   +1 more source

Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity

Obesity Science & Practice, 2020
Summary Objective There is an unmet medical need for a safe and effective weight loss product with minimal systemic side‐effects. In this study, the effect of a novel modified‐release fixed‐dose combination of orlistat and acarbose (MR‐OA) was compared ...
Ulf Holmbäck, Anders Forslund, Stefan Grudén, Göran Alderborn, Arvid Söderhäll, Per M. Hellström, Hans Lennernäs   +6 more
doaj   +1 more source

Development of the Composition and Technology of Orally Dispersed Tablets Based on Ethylthiobenzimidazole Fumarate

Разработка и регистрация лекарственных средств, 2022
Introduction. The article presents the results of the development of the composition and technology of orally dispersed tablets of ethylthiobenzimidazole fumarate – a new actoprotective and adaptogenic agent.Aim.
I. D. Kasymov, A. V. Basevich, A. L. Marchenko, V. A. Vainshtein   +3 more
doaj   +1 more source

Development of a Gastro-retentive Dosage Form of a New Promising Anti-tuberculosis Drug Macozinone

Разработка и регистрация лекарственных средств, 2021
Introduction. Due to increase in the frequency of detecting cases of tuberculosis caused by strains of mycobacteria with resistance not only to traditional, but also recently introduced into clinical circulation anti-tuberculosis drugs, it is urgent to ...
V. G. Nesterenko, R. N. Bolgarin, B. A. Rudoy, D. K. Salakhetdinov, Yu. G. Kazaishvili, V. S. Scherbakova, N. A. Nikitina, Yu. V. Medvedev, E. N. Fisher, E. A. Malashenko, I. E. Shohin   +10 more
doaj   +1 more source

Production and Characterization of Chitosan–Polyanion Nanoparticles by Polyelectrolyte Complexation Assisted by High-Intensity Sonication for the Modified Release of Methotrexate

Pharmaceuticals, 2020
A promising strategy to improve the effectivity of anticancer treatment and decrease its side effects is to modulate drug release by using nanoparticulates (NPs) as carriers.
Yhors Ciro, John Rojas, Maria J. Alhajj, Gustavo A. Carabali, Constain H. Salamanca   +4 more
doaj   +1 more source

Hydrophilic Excipient-Independent Drug Release from SLA-Printed Pellets

Pharmaceutics, 2021
Three-dimensional (3D) printing technology, specifically stereolithography (SLA) technology, has recently created exciting possibilities for the design and fabrication of sophisticated dosages for oral administration, paving a practical way to precisely ...
Lei Xu, Qingliang Yang, Wei Qiang, Huijie Li, Weizhen Zhong, Siying Pan, Gensheng Yang   +6 more
doaj   +1 more source

Controlled release of anticancer drugs via the magnetic magnesium iron nanoparticles modified by graphene oxide and polyvinyl alcohol: Paclitaxel and docetaxel [PDF]

Nanomedicine Journal, 2021
Objective(s): Paclitaxel (PTX) and docetaxel (DTX) belong to the family of taxanes drugs which have been employed for treatment of ovarian, breast, lung, head, neck, gastric, pancreatic, bladder, prostate and cervical cancer.
Ahmad Gholami, Biuck Habibi, Amir Abbas Matin, Naser Samadi   +3 more
doaj   +1 more source

Modified Sulfanilamide Release from Intelligent Poly(N-isopropylacrylamide) Hydrogels

Pharmaceutics, 2023
The aim of this study was to examine homopolymeric poly(N-isopropylacrylamide), p(NIPAM), hydrogels cross-linked with ethylene glycol dimethacrylate as carriers for sulfanilamide.
Ana Dinić, Vesna Nikolić, Ljubiša Nikolić, Snežana Ilić-Stojanović, Stevo Najman, Maja Urošević, Ivana Gajić   +6 more
doaj   +1 more source

Influence of High, Disperse API Load on Properties along the Fused-Layer Modeling Process Chain of Solid Dosage Forms

Pharmaceutics, 2019
In order to cope with the increasing number of multimorbid patients due to demographic changes, individualized polypill solutions must be developed. One promising tool is fused layer modeling (FLM) of dosage forms with patient-specific dose combinations ...
Marius Tidau, Arno Kwade, Jan Henrik Finke   +2 more
doaj   +1 more source