Results 11 to 20 of about 7,431 (174)

Correction to "Impact of vaccination with third generation modified vaccinia Ankara and sexual behaviour on mpox incidence in men who have sex with men: analysis among participants of the ANRS-174 DOXYVAC trial" [The Lancet Regional Health-Europe 45, October 2024, 101020]. [PDF]

Lancet Reg Health Eur
Ghosn J, Assoumou L, Ouattara M, Rubenstein E, Pialoux G, Katlama C, Surgers L, Duvivier C, Pavie J, Viard JP, Algarte-Genin M, Gibowski S, Ollivier M, Costagliola D, Molina JM.   +14 more
europepmc   +2 more sources

The significance of the omentum in locoregional immunotherapy for peritoneal carcinomatosis

OncoImmunology, 2023
Our recent research has unveiled the potential of locoregional immunotherapy. Cytokine-armored viral vectors, such as modified vaccinia virus Ankara vector encoding single-chain interleukin-12 (MVA.scIL-12), can target the omentum and elicit a robust ...
Ángela Bella, Ignacio Melero, Pedro Berraondo, Fernando Aranda   +3 more
doaj   +1 more source

Nanopore sequencing and de novo assembly of a misidentified Camelpox vaccine reveals putative epigenetic modifications and alternate protein signal peptides

Scientific Reports, 2021
DNA viruses can exploit host cellular epigenetic processes to their advantage; however, the epigenome status of most DNA viruses remains undetermined.
Zack Saud, Matthew D. Hitchings, Tariq M. Butt   +2 more
doaj   +1 more source

A Deleted Deletion Site in a New Vector Strain and Exceptional Genomic Stability of Plaque-Purified Modified Vaccinia Ankara (MVA). [PDF]

Virol Sin, 2020
Jordan I, Horn D, Thiele K, Haag L, Fiddeke K, Sandig V.   +5 more
europepmc   +3 more sources

MERS-CoV‒Specific T-Cell Responses in Camels after Single MVA-MERS-S Vaccination

Emerging Infectious Diseases, 2023
We developed an ELISPOT assay for evaluating Middle East respiratory syndrome coronavirus (MERS-CoV)‒specific T-cell responses in dromedary camels. After single modified vaccinia virus Ankara-MERS-S vaccination, seropositive camels showed increased ...
Christian Meyer zu Natrup, Lisa-Marie Schünemann, Giulietta Saletti, Sabrina Clever, Vanessa Herder, Sunitha Joseph, Marina Rodriguez, Ulrich Wernery, Gerd Sutter, Asisa Volz   +9 more
doaj   +1 more source

Comparison of Recombinant MVA Selection Methods Based on F13L, D4R and K1L Genes

Viruses, 2022
Modified vaccinia Ankara (MVA) is a promising vaccine vector due to its highly attenuated phenotype and good immunogenicity. However, obtaining a new recombinant MVA remains a tedious and laborious procedure involving many rounds of plaque purification ...
Irina V. Antoshkina, Dina V. Glazkova, Felix A. Urusov, Elena V. Bogoslovskaya, German A. Shipulin   +4 more
doaj   +1 more source

Vaccinia E5 is a major inhibitor of the DNA sensor cGAS

Nature Communications, 2023
The DNA sensor cyclic GMP-AMP synthase (cGAS) is critical in host antiviral immunity. Vaccinia virus (VACV) is a large cytoplasmic DNA virus that belongs to the poxvirus family.
Ning Yang, Yi Wang, Peihong Dai, Tuo Li, Christian Zierhut, Adrian Tan, Tuo Zhang, Jenny Zhaoying Xiang, Alban Ordureau, Hironori Funabiki, Zhijian Chen, Liang Deng   +11 more
doaj   +1 more source

Safety and Immunogenicity of Adenovirus and Poxvirus Vectored Vaccines against a Mycobacterium Avium Complex Subspecies

Vaccines, 2021
Heterologous prime-boost strategies are known to substantially increase immune responses in viral vectored vaccines. Here we report on safety and immunogenicity of the poxvirus Modified Vaccinia Ankara (MVA) vectored vaccine expressing four Mycobacterium
Pedro M. Folegatti, Amy Flaxman, Daniel Jenkin, Rebecca Makinson, Lucy Kingham-Page, Duncan Bellamy, Fernando Ramos Lopez, Jonathan Sheridan, Ian Poulton, Jeremy Aboagye, Nguyen Tran, Celia Mitton, Rachel Roberts, Alison M. Lawrie, Adrian V. S. Hill, Katie J. Ewer, Sarah Gilbert   +16 more
doaj   +1 more source

Developing a Feline Immunodeficiency Virus Subtype B Vaccine Prototype Using a Recombinant MVA Vector

Vaccines, 2022
The feline immunodeficiency virus (FIV) is a retrovirus with global impact and distribution, affecting both domestic and wild cats. This virus can cause severe and progressive immunosuppression culminating in the death of felids.
Luis A. F. Andrade, Alice F. Versiani, Edel F. Barbosa-Stancioli, Jenner K. P. dos Reis, Jordana Grazziela A. C. dos Reis, Flavio G. da Fonseca   +5 more
doaj   +1 more source

Single Immunization of a Vaccine Vectored by a Novel Recombinant Vaccinia Virus Affords Effective Protection Against Respiratory Syncytial Virus Infection in Cotton Rats

Frontiers in Immunology, 2021
Respiratory syncytial virus (RSV) is a leading cause of respiratory infections worldwide and disease management measures are hampered by the lack of a safe and effective vaccine against the infection.
Marsha S. Russell, Sathya N. Thulasi Raman, Caroline Gravel, Wanyue Zhang, Wanyue Zhang, Annabelle Pfeifle, Annabelle Pfeifle, Wangxue Chen, Gary Van Domselaar, David Safronetz, Michael Johnston, Michael Johnston, Simon Sauve, Lisheng Wang, Michael Rosu-Myles, Michael Rosu-Myles, Jingxin Cao, Xuguang Li, Xuguang Li   +18 more
doaj   +1 more source