Results 1 to 10 of about 516 (69)
This illustration depicts a comprehensive strategy against monkeypox, showcasing its transmission, symptoms, and prevention. Centralized around nanomaterials and biosensors, it integrates early screening, Internet of Things, vaccination, and community involvement through collaboration among healthcare workers, scientists, researchers, social groups ...
Vishal Chaudhary+3 more
wiley +1 more source
Summary The immunosuppressive and immunomodulatory treatment of dermatological patients necessitates the regular review and updating of standard vaccinations and vaccines indicated for specific conditions. The German Standing Committee on Vaccination (STIKO) at the Robert Koch Institute regularly publishes evidence‐based vaccination recommendations ...
Johanna Stoevesandt+3 more
wiley +1 more source
Revolution of AAV in Drug Discovery: From Delivery System to Clinical Application
ABSTRACT Adeno‐associated virus (AAV) is a non‐enveloped DNA virus infecting a wide variety of species, tissues, and cell types, which is recognized as a safe and effective method for delivering therapeutic transgenes. AAV vector is the most popular viral gene delivery system in clinical delivery systems with unique and multiple advantages, such as ...
Ling Yin+6 more
wiley +1 more source
Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics
This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold+2 more
wiley +1 more source
Passive Immunization in the Prevention and Treatment of Viral Infections
The development of new technologies for generating monoclonal antibodies has made it possible to extend the use of monoclonal antibodies for controlling viral infections. Here, we discuss the advances in antibody cloning techniques and the current use of passive immunization both as a preventative measure and treatment of viral infection.
Romila Moirangthem, Yotam Bar‐On
wiley +1 more source
Marburg Virus Disease: A Narrative Review
ABSTRACT Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re‐emergence of MARV as a growing concern for public health.
Arash Letafati+4 more
wiley +1 more source
Monkeypox Virus Subverts the Inflammatory Response of Macrophages at the Maternal‐Fetal Interface
ABSTRACT Monkeypox is a viral zoonosis caused by the monkeypox virus (MPXV). Although the virus was identified decades ago, human immunity to MPXV infection has not been widely characterized. During MPXV infection, macrophages are recruited at the site of infection and are thought to contribute to the spread of the virus.
Jonatane Andrieu+7 more
wiley +1 more source
Advancing ORFV‐Based Therapeutics to the Clinical Stage
ABSTRACT The Orf virus (ORFV) is the prototype member of the parapoxvirus family and has long been recognized for its robust immunogenicity, favourable safety profile and its ability to stimulate both cellular and humoural immune responses without inducing significant anti‐vector immunity.
Matthias Helmold, Ralf Amann
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Men who have sex with men (MSM), with a median age of 32 (27–37) years, from China's coastal or developed regions, are the “main mpox‐affected” population. HIV‐positive mpox patients showed more severe manifestations, with elevated aspartate transaminase and C‐reactive protein levels, reduced CD4+ T and NK (natural killer) cell counts versus HIV ...
Hankun Hu+18 more
wiley +1 more source
The monkeypox virus (MPXV) has spread to many countries and caused thousands of infections all over the world. This review comprehensively introduces the biology, epidemiological characteristics of MPXV, and clinical manifestations of Mpox. The approaches for diagnosis, treatment, and prevention are also introduced, aiming to improve the general ...
Lin Jiang+15 more
wiley +1 more source