Results 181 to 190 of about 11,489 (193)

Multiantigenic Modified Vaccinia Virus Ankara Vaccine Vectors To Elicit Potent Humoral and Cellular Immune Reponses against Human Cytomegalovirus in Mice. [PDF]

J Virol, 2018
Chiuppesi F, Nguyen J, Park S, Contreras H, Kha M, Meng Z, Kaltcheva T, Iniguez A, Martinez J, La Rosa C, Wussow F, Diamond DJ.   +11 more
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Modified Vaccinia Virus Ankara Antibody [PDF]

, 2020
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Development of Modified Vaccinia Virus Ankara-based Influenza Vaccines

, 2018
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Protective efficacy of Modified Vaccinia virus Ankara in preclinical studies

Vaccine, 2013
Modified Vaccinia virus Ankara (MVA) is a tissue culture-derived, highly attenuated strain of vaccinia virus (VACV) exhibiting characteristic defective replication in cells from mammalian hosts. In the 1960s MVA was originally generated as a candidate virus for safer vaccination against smallpox.
Asisa Volz, Gerd Sutter
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Vaccinia Vectors as Candidate Vaccines: The Development of Modified Vaccinia Virus Ankara for Antigen Delivery

Current Drug Target -Infectious Disorders, 2003
Vaccinia viruses engineered to express foreign genes are powerful vectors for production of recombinant proteins. Originating from highly efficacious vaccines securing world-wide eradication of smallpox, the most appealing use of vaccinia vectors is to serve as vaccine delivery system for heterologous antigens.
Caroline Staib, Gerd Sutter
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Safety of modified vaccinia virus Ankara (MVA) in immune-suppressed macaques

Vaccine, 2001
Modified vaccinia virus Ankara (MVA)-based recombinant viruses have been shown to be potent vaccine candidates for several infectious and neoplastic diseases. Since a major application of these live, replication-deficient vectors would be their use in immunocompromised or potentially immunocompromised individuals, a preclinical safety study was carried
Hubert G. M. Niesters, Albert D. M. E. Osterhaus, Linda S. Wyatt, Koert J. Stittelaar, Geert van Amerongen, Bernard Moss, Thijs Kuiken, Theo H. van der Kwast, Helma W. Vos, Rik L. de Swart, Pim van Schalkwijk   +10 more
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Substitution of Vaccinia Virus Elstree by Modified Vaccinia Virus Ankara to test the Virucidal Efficacy of Chemical Disinfectants

Zoonoses and Public Health, 2008
SummaryAfter the eradication of variola in 1980, the smallpox vaccination was considered to be no longer required and was subsequently abandoned mainly because of possible adverse effects of vaccinia virus especially in first‐time vaccinees. Despite a growing number of humans without immunity against vaccinia virus, vaccinia virus Lister Elstree (VACV)
Sandra Essbauer, U. Truyen, Sonja Hartnack   +2 more
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Generation and Production of Modified Vaccinia Virus Ankara (MVA) as a Vaccine Vector

2017
The smallpox vaccine based on the vaccinia virus was successfully used to eradicate smallpox, but although very effective, it was a very reactogenic vaccine and responsible for the deaths of one to two people per million vaccinated. Modified Vaccinia virus Ankara (MVA) is an attenuated derivative, also used in the smallpox eradication campaign and now ...
Vincent Pavot, Sarah C. Gilbert, Sarah Sebastian, Jake Matthews, A Turner   +4 more
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Modified Vaccinia virus Ankara: Innate immune activation and induction of cellular signalling

Vaccine, 2013
Attenuated poxviruses are currently under development as vaccine vectors against a number of diseases including, influenza, HIV, malaria and tuberculosis. Modified Vaccinia virus Ankara (MVA) is an attenuated, replication deficient vaccinia virus (VACV) strain which, similar to replication competent VACV, is highly immunogenic.
Philip J.R. Price, Lino E. Torres-Domínguez, Christine Brandmüller, Gerd Sutter, Michael H. Lehmann   +4 more
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Modified Vaccinia Virus Ankara as Vaccine Vectors in Human and Veterinary Medicine

Future Virology, 2014
Disease prevention through vaccination is one of the most important achievements of medicine. Today, we have a substantial number of vaccines against a variety of pathogens. In this context, poxviruses and vaccinology are closely related, as the birth of modern vaccinology was marked by the use of poxviruses as immunogens and so was the eradication of ...
Danielle So Daian, Bárbara Resende Quinan, Fabiana Magalhães Coelho, Flávio Guimarães da Fonseca, Flávio Guimarães da Fonseca   +4 more
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