Results 21 to 30 of about 12,579 (242)

Rapid Development of Modified Vaccinia Virus Ankara (MVA)-Based Vaccine Candidates Against Marburg Virus Suitable for Clinical Use in Humans. [PDF]

Vaccines (Basel)
Tscherne A, Kalodimou G, Kupke A, Rohde C, Freudenstein A, Jany S, Kumar S, Sutter G, Krähling V, Becker S, Volz A.   +10 more
europepmc   +3 more sources

Safety and immunogenicity of a synthetic multiantigen modified vaccinia virus Ankara-based COVID-19 vaccine (COH04S1): an open-label and randomised, phase 1 trial. [PDF]

Lancet Microbe, 2022
Chiuppesi F, Zaia JA, Frankel PH, Stan R, Drake J, Williams B, Acosta AM, Francis K, Taplitz RA, Dickter JK, Dadwal S, Puing AG, Nanayakkara DD, Ash P, Cui Y, Contreras H, La Rosa C, Tiemann K, Park Y, Medina J, Iniguez A, Zhou Q, Karpinski V, Johnson D, Faircloth K, Kaltcheva T, Nguyen J, Kha M, Nguyen VH, Francisco SO, Grifoni A, Wong A, Sette A, Wussow F, Diamond DJ.   +34 more
europepmc   +3 more sources

Vaccination directed against the human endogenous retrovirus-K envelope protein inhibits tumor growth in a murine model system [PDF]

, 2013
Human endogenous retrovirus (HERV) genomes are chromosomally integrated in all cells of an individual. They are normally transcriptionally silenced and transmitted only vertically. Enhanced expression of HERV-K accompanied by the emergence of anti-HERV-K-
Büchner, Sarah M., Fischer, Katrin, Kraus, Benjamin, Löwer, Roswitha, Schnierle, Barbara S., Sliva, Katja, Wels, Winfried S.   +6 more
core   +28 more sources

Expression of an Efficient Selection Marker Out of a Duplicated Site in the ITRs of a Modified Vaccinia Virus Ankara (MVA). [PDF]

Vaccines (Basel)
Abidi S, Elhazaz Fernandez A, Seehase N, Hanisch L, Karlas A, Sandig V, Jordan I.   +6 more
europepmc   +2 more sources

Improved Host Range Selection for Recombinant Modified Vaccinia Virus Ankara [PDF]

BioTechniques, 2003
Caroline Staib, Marianne Löwel, Volker Erfle, Gerd Sutter   +3 more
doaj   +3 more sources

Purification of modified vaccinia virus Ankara from suspension cell culture [PDF]

BMC Proceedings, 2015
Background A spectrum of viral vaccines, including the annual 620 million doses of trivalent influenza vaccines, are being produced in embryonated eggs of pharmaceutical quality, or with primary cells derived from such eggs [1,2]. Regulatory guidelines and experience for these processes are established and proven against time for 75 years [1]. However,
Ingo Jordan, Diana Weimer, Stefan Iarusso, Holger Bernhardt, Verena Lohr, Volker Sandig   +5 more
openalex   +2 more sources

Immunogenicity and Safety of Modified Vaccinia Ankara (MVA) Vaccine—A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Vaccines, 2023
Prevention of mpox has become an important public health interest. We aimed to evaluate the safety and immunogenicity of the Modified Vaccinia Ankara (MVA) vaccine. We conducted a systematic review and meta-analysis of randomized-controlled trials (RCTs)
Lior Nave, Ili Margalit, Noam Tau, Ido Cohen, Dana Yelin, Florian Lienert, Dafna Yahav   +6 more
doaj   +1 more source

A vital gene for modified vaccinia virus Ankara replication in human cells. [PDF]

Proc Natl Acad Sci U S A, 2020
Vaccinia virus (VACV), the prototype orthopoxvirus, is the first live viral vaccine used to protect against smallpox, one of the most feared infectious diseases of humans (1). This outstanding achievement was possible because even as the various orthopoxviruses evolved and diversified they often retained major parts of their virion composition in ...
Sutter G.
europepmc   +4 more sources

The significance of the omentum in locoregional immunotherapy for peritoneal carcinomatosis

OncoImmunology, 2023
Our recent research has unveiled the potential of locoregional immunotherapy. Cytokine-armored viral vectors, such as modified vaccinia virus Ankara vector encoding single-chain interleukin-12 (MVA.scIL-12), can target the omentum and elicit a robust ...
Ángela Bella, Ignacio Melero, Pedro Berraondo, Fernando Aranda   +3 more
doaj   +1 more source

Nanopore sequencing and de novo assembly of a misidentified Camelpox vaccine reveals putative epigenetic modifications and alternate protein signal peptides

Scientific Reports, 2021
DNA viruses can exploit host cellular epigenetic processes to their advantage; however, the epigenome status of most DNA viruses remains undetermined.
Zack Saud, Matthew D. Hitchings, Tariq M. Butt   +2 more
doaj   +1 more source