Results 81 to 90 of about 12,579 (242)

Effects of MVA85A vaccine on tuberculosis challenge in animals: systematic review [PDF]

, 2015
Background The existing Bacillus Calmette–Guérin (BCG) vaccination provides partial protection against tuberculosis (TB). The modified vaccinia ankara virus-expressing antigen 85A (MVA85A) aims to boost BCG immunity.
Garner, Paul, Kashangura, Rufaro, Sena, Emily, Young, Taryn   +3 more
core   +3 more sources

Protective vaccination with hepatitis C virus NS3 but not core antigen in a novel mouse challenge model [PDF]

, 2008
BACKGROUND: Efficient vaccines against hepatitis C virus (HCV) infection are urgently needed. Vaccine development has been hampered by the lack of suitable small animal models to reliably test the protective capacity of immmunization. METHODS: We used
Adler, Adler, Arribillaga, Battegay, Bergqvist, Bruna-Romero, Cerny, Diepolder, Diepolder, Eisen-Vandervelde, El-Gogo, Fischer, Flano, Flano, Folgori, Frelin, Geissler, Gerlach, Gonzalez-Aseguinolaza, Grakoui, Gruener, Houghton, Inchauspe, Kato, Kittlesen, Large, Major, Marques, McLauchlan, Messerle, Nascimbeni, Nash, Rollier, Schirren, Shirai, Shoukry, Staib, Staib, Staib, Staib, Stevenson, Stewart, Sunil-Chandra, Takaki, Thimme, Ulsenheimer, Usherwood, Virgin, Virgin, Weck, Willer, Yao   +51 more
core   +1 more source

Recurrent Respiratory Papillomatosis Foundation Position Statement on the Management of Adults With RRP

The Laryngoscope, EarlyView.
ABSTRACT Objective With regulatory approval of HPV‐specific immunotherapy for recurrent respiratory papillomatosis (RRP) and growing experience with systemic bevacizumab, a management algorithm incorporating these medical treatments is warranted. Data Sources and Methods RRP Foundation (RRPF) Key Opinion Leaders offer a proposed management algorithm ...
Simon R. Best, Aaron D. Friedman, Clark A. Rosen, Robert T. Sataloff, Laura A. Matrka, H. Steven Sims, David E. Rosow, Nabil F. Saba, David G. Lott, Adam M. Klein, Ted Mau, Milan R. Amin, Kathryn A. Wikenheiser‐Brokamp, Scott M. Norberg, Kim McClellan, Geoffrey D. Young, Clint T. Allen, on behalf of the Recurrent Respiratory Papillomatosis Foundation   +17 more
wiley   +1 more source

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

The Block in Assembly of Modified Vaccinia Virus Ankara in HeLa Cells Reveals New Insights into Vaccinia Virus Morphogenesis [PDF]

Journal of Virology, 2002
ABSTRACT It has previously been shown that upon infection of HeLa cells with modified vaccinia virus Ankara (MVA), assembly is blocked at a late stage of infection and immature virions (IVs) accumulate (G. Sutter and B. Moss, Proc. Natl. Acad. Sci. USA 89:10847-10851, 1992).
M Carmen, Sancho, Sibylle, Schleich, Gareth, Griffiths, Jacomine, Krijnse-Locker   +3 more
openaire   +2 more sources

Human and bovine respiratory syncytial virus vaccine research and development [PDF]

, 2008
Human (HRSV) and bovine (BRSV) respiratory syncytial viruses (RSV) are two closely related viruses, which are the most important causative agents of respiratory tract infections of young children and calves, respectively.
Deplanche, Martine, Meyer, Gilles, Schelcher, François   +2 more
core   +2 more sources

Mpox and the Ethics of Outbreak Management: Lessons for Future Public Health Crises

Developing World Bioethics, EarlyView.
ABSTRACT Mpox, first identified in captive monkeys in 1958 and recognized in humans by 1970 in the Democratic Republic of Congo, was historically confined to sporadic zoonotic outbreaks in Central and West Africa. These outbreaks, often driven by rodent‐to‐human transmission in resource‐limited settings, reflect persistent systemic health disparities ...
Adetayo E. Obasa, Marietjie Botes, Anita Kleinsmidt, Ciara Staunton   +3 more
wiley   +1 more source

Humoral epitope dominance and immune imprinting by SARS‐CoV‐1 and SARS‐CoV‐2 vaccines

Immunology &Cell Biology, EarlyView.
We investigated Modified Vaccinia Ankara (MVA) vaccine candidates expressing the SARS‐CoV‐1 or SARS‐CoV‐2 Spike, as a primary or booster immunization, for their ability to induce antibodies targeting different epitopes on the SARS‐CoV‐2 RBD and broad cross‐reactive or cross‐neutralizing responses in C57BL/6 and antibody humanized (Ig‐humanized) mice ...
Deborah L Burnett, Ania Moxon, Anupriya Aggarwal, Katherine JL Jackson, Catherine Cotter, Anouschka Akerman, Amanda Russell, Rachel Kalman, David Langley, Jake Y Henry, Daniel Christ, Rowena A Bull, Robert Brink, Anthony D Kelleher, Hans‐Martin Jäck, Stuart Turville, Bernard Moss, Christopher C Goodnow   +17 more
wiley   +1 more source

Evaluation of modified vaccinia virus Ankara based recombinant SARS vaccine in ferrets

Vaccine, 2005
Severe acute respiratory syndrome (SARS) caused by a newly identified coronavirus (SARS-CoV) remains a threat to cause epidemics as evidenced by recent sporadic cases in China. In this communication, we evaluated the efficacy and safety of two SARS vaccine candidates based on the recombinant modified vaccinia Ankara (MVA) expressing SARS-CoV spike or ...
Czub, Markus, Weingartl, Hana, Czub, Stefanie, He, Runtao, Cao, Jingxin   +4 more
openaire   +2 more sources

Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe, Tamara Zoran, Marylyn Martina Addo   +2 more
wiley   +1 more source