Results 101 to 110 of about 1,839,177 (303)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

"Modified" Thoracoplasty [PDF]

Thorax, 1955
T H, SELLORS, J W, JACKSON, J G, CALLANAN   +2 more
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Modifying of iron cast melt

Литьë и металлургия, 2000
The article considers influence of single and complex admixtures of graphitizing modifiers and elements increasing supercooling as well as effect of the level of eutecticity, carbon content and cooling speed on the eutectic crystallization process ...
L. Z. Pisarenko
doaj  

Modifying gene expression through passive forces

eLife
The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.
Sarah Hallstein, Julian König
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Modified Syphilis [PDF]

BMJ, 1874
openaire   +5 more sources

COMPLEX MODIFYING OF LOW-CARBON STEEL

Литьë и металлургия, 2010
The received results testify that introduction into composition complex of modifiier of carbide-forming and surfactant elements promotes increasing of its efficiency on macroand microstructure of steel.
O. S. Komarov, V. I. Volosatikov, D. O. Komarov, V. D. Tuljev, N. I. Urbanovich   +4 more
doaj  

Modifying Pharmacy Enrollments by Employment Realities

INNOVATIONS in Pharmacy
Objective: The objective of this commentary is to consider the fluctuations in pharmacy school enrollments and to review some of the strategies employed in other health care professions as well as to consider policies that might lead to a closer balance
Crystal Lloyd, Albert Wertheimer, Thandeka Bissasor, Phat Truong, Nile Khanfar   +4 more
doaj   +1 more source

Scale dynamical origin of modification or addition of potential in mechanics. A possible framework for the MOND theory and the dark matter

, 2016
Using our mathematical framework developed in \cite{cresson-pierret_scale} called \emph{scale dynamics}, we propose in this paper a new way of interpreting the problem of adding or modifying potentials in mechanics and specifically in galactic dynamics ...
Pierret, Frédéric
core