Results 111 to 120 of about 1,820,346 (284)

Modifying of iron cast melt

Литьë и металлургия, 2000
The article considers influence of single and complex admixtures of graphitizing modifiers and elements increasing supercooling as well as effect of the level of eutecticity, carbon content and cooling speed on the eutectic crystallization process ...
L. Z. Pisarenko
doaj  

Dynamic Virtual Join Point Dispatch [PDF]

, 2006
Conceptually, join points are points in the execution of a program and advice is late-bound to them. We propose the notion of virtual join points that makes this concept explicit not only at a conceptual, but also at implementation level.
Bockisch, Christoph, Hauptmann, Michael, Mezini, Mira   +2 more
core   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

ON MODIFYING OF HYPEREUTECTIC SILUMINS

Литьë и металлургия, 2008
It is shown that efficiency of hypereutectic silumin is determined in general by deoxidizing ability of modifiers.
V. Ju. Stetsenko
doaj  

Epigenome Modifying Tools In Asthma [PDF]

, 2015
Adcock,, Brook, PO, Durham, AL, Perry, M
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

INCREASE OF THE MODIFYING EFFICIENCY

Литьë и металлургия, 2006
Short review and analysis of the basic nine well known ways of the metals and alloys modifying are given. It is shown that casting by means of mixing of one- and two-phase melts, casting by quenching hardening, casting in crystallyzer with jet cooling is
E. I. Marukovich, V. Ju. Stetsenko
doaj  

Modifying gene expression through passive forces

eLife
The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.
Sarah Hallstein, Julian König
doaj   +1 more source