Results 71 to 80 of about 1,820,346 (284)
Evolving targets for lipid‐modifying therapy
EMBO Molecular Medicine, 2014 The pathogenesis and progression of atherosclerosis are integrally connected to the concentration and function of lipoproteins in various classes. This review examines existing and emerging approaches to modify low‐density lipoprotein and lipoprotein (a),
Rose Q Do +2 more
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CRISPR: modifying the life science landscape
BioTechniques, 2016 From lampreys to human stem cells, the CRISPR/Cas9 system is challenging our notions of what is possible with genome editing. Nathan Blow talks to researchers pushing the boundaries of CRISPR/Cas9 technology to expand our understanding of biology.
Nathan Blow
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
beta-1,3-glucan modifying enzymes in Aspergillus fumigatus
Frontiers in Microbiology, 2013 In Aspergillus fumigatus like in other filamentous ascomycetes, beta-1,3-glucan constitutes a prominent cell wall component being responsible for rigidity of the cell wall structure. In filamentous fungi, softening of the cell wall is absolutely required
Isabelle eMouyna +2 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
MAIN PROBLEMS OF MODERN MODIFYING OF ALLOYS. SOLUTIONS
Литьë и металлургия, 2016 It is shown that the main problems of modern modifying of alloys are connected with the air atmosphere and use of impurity modifiers. For the solution of these problems it is necessary to use the accelerated hardening, fine-crystalline furnace charge and
V. Yu. Stetsenko
doaj
Modifying Hebbian Network for Text Cipher
مجلة بغداد للعلوم, 2011 The objective of this work is to design and implement a cryptography system that enables the sender to send message through any channel (even if this channel is insecure) and the receiver to decrypt the received message without allowing any intruder to ...
Baghdad Science Journal
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Roll function in a flight simulator [PDF]
, 1972 Method introduces roll into the flying-spot scanner by modifying the scanning ...
Brain, A. E.
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FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source