Results 81 to 90 of about 1,820,346 (284)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Deoxidation impact on the impurity index of heat resistant steel 40H15N7G7F2MS
Metalurgija, 2017 Analyzing failure causes of the parts made of heat resistant steel shows that one of the defining factors impacting the properties is concentration of harmful impurities both dissolved in steel and being in the form of nonmetallic inclusions. The latter,
A. Z. Issagulov +4 more
doaj
Medicare Part D: Simplifying the Program and Improving the Value of Information for Beneficiaries [PDF]
, 2008 Examines options for simplifying Medicare's prescription drug benefit, including streamlining benefit procedures and descriptions; further standardizing benefit parameters, especially cost-sharing rules; and modifying rules on plan ...
Jack Hoadley
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Frontiers in Microbiology, 2018 The incidence and prevalence of non-tuberculous mycobacterial (NTM) infections have been increasing worldwide and lately led to an emerging public health problem.
Sakshi Luthra +3 more
doaj +1 more source
Solar X-ray spectrum reproduced in vacuum [PDF]
, 1967 Desired low energy X rays are produced by modifying commercial ion tubes and combining them with standard power supplies and control circuitry.
Erdman, C. A., Kirchner, L. P.
core +1 more source
Pressure-induced commensurate stacking of graphene on boron nitride
, 2016 Combining atomically-thin van der Waals materials into heterostructures provides a powerful path towards the creation of designer electronic devices. The interaction strength between neighboring layers, most easily controlled through their interlayer ...
LeRoy, Brian J. +4 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Revisiting the modifying environment approach
Scottish Journal of Residential Child Care, 2010 Theory is a fundamental piece of professional child and youth care practice, and finding useful, life-space applicable theory that addresses the complex issues presented by the young people in child and youth care is a continual challenge.
Jack Phelan
doaj +1 more source
Modifying Fragility and Collective Motion in Polymer Melts with Nanoparticles
, 2011 We investigate the impact of nanoparticles (NP) on the fragility and cooperative string-like motion in a model glass-forming polymer melt by molecular dynamics simulation.
Douglas, Jack F., Starr, Francis W.
core +1 more source