Results 41 to 50 of about 1,125,805 (286)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Design of cooling system in space solar array simulator

Dianzi Jishu Yingyong, 2019
For the high power solar array simulator, the requirements such as high power, miniaturization and modularization are higher. In this paper the total power of the simulator is 2.4 kW with the chassis height is no more than 2U.
Zhang Jian, Wang Zicai, Zhang Hua, Zhang Donglai   +3 more
doaj   +1 more source

Siegel modular forms of genus 2 and level 2

, 2015
We study vector-valued Siegel modular forms of genus 2 and level 2. We describe the structure of certain modules of vector-valued modular forms over rings of scalar-valued modular forms.Comment: 46 pages.
Cléry, Fabien, Grushevsky, Samuel, van der Geer, Gerard   +2 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Small molecule autoencoders: architecture engineering to optimize latent space utility and sustainability

Journal of Cheminformatics
Autoencoders are frequently used to embed molecules for training of downstream deep learning models. However, evaluation of the chemical information quality in the latent spaces is lacking and the model architectures are often arbitrarily chosen ...
Marie Oestreich, Iva Ewert, Matthias Becker   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

A modular method for the extraction of DNA and RNA, and the separation of DNA pools from diverse environmental sample types

Frontiers in Microbiology, 2015
A method for the extraction of nucleic acids from a wide range of environmental samples was developed. This method consists of several modules, which can be individually modified to maximize yields in extractions of DNA and RNA or separations of DNA ...
Mark Alexander Lever, Mark Alexander Lever, Andrea eTorti, Philip eEickenbusch, Alexander Bryce Michaud, Tina eŠantl-Temkiv, Bo Barker Jørgensen   +6 more
doaj   +1 more source

Modular Markovian Logic [PDF]

, 2011
We introduce Modular Markovian Logic (MML) for compositional continuous-time and continuous-space Markov processes. MML combines operators specific to stochastic logics with operators reflecting the modular structure of the models, similar to those used by spatial and separation logics.
Cardelli L., Larsen K.G., Mardare R.
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Experimental Control of Two Connected Fixed Wing Aircraft

Aerospace, 2018
This paper investigates the design and flight test of two fixed wing aircraft connected at the wing tips. Connecting multiple aircraft introduces flexible modes into a typically rigid body system.
Collin Carithers, Carlos Montalvo
doaj   +1 more source