Results 91 to 100 of about 61,255 (309)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Design Strategies for Modular Demountable Building Products Oriented to Design for Manufacturing and Assembly: A Case Study of M-Box1.0

open access: yesBuildings
With the advancement of building industrialization and sustainable development, modular demountable buildings, as an efficient and environmentally friendly form, show significant potential in scenarios such as emergency housing and rural construction ...
Meng Wang   +5 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Towards Greener Tourism: Evaluation of the Energy Performance and Self-Sufficiency in a Modular Dwelling Across Spanish Territory

open access: yesBuildings
Repurposing shipping containers to construct modular buildings is an emerging trend that contributes to a more sustainable building sector. In the tourism sector, they enable low-impact, relocatable accommodation adaptable to diverse environments ...
Javier López-Bértolo   +4 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Simulation of modular building construction [PDF]

open access: yes2008 Winter Simulation Conference, 2008
Osama M. Mohsen   +4 more
openaire   +1 more source

Preparation and provision of building information for planning within existing built contexts [PDF]

open access: yes, 2004
A prerequisite for planning within existing built contexts is precise information regarding the building substance, its construction and materials, possible damages and any modifications and additions that may have occurred during its lifetime. Using the
Petzold, Frank   +2 more
core   +1 more source

Investigation of the Energy Performance of a Novel Modular Solar Building Envelope

open access: yesEnergies, 2017
The major challenges for the integration of solar collecting devices into a building envelope are related to the poor aesthetic view of the appearance of buildings in addition to the low efficiency in collection, transportation, and utilization of the ...
Gang Ren   +4 more
doaj   +1 more source

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