Results 51 to 60 of about 43,547 (311)

Theoretical and Simulation-Based Approach to BIPV Systems Integrated with Modular Building

Energies
This study presents a simulation-based analysis of a steel modular building that integrates technologies that support the energy transition in the built environment.
Julia Brenk, Barbara Ksit, Bożena Orlik-Kożdoń   +2 more
doaj   +1 more source

Modular residential buildings as engineering hybrids

Current problems of architecture and urban planning, 2023
The article discusses the varieties of engineering hybrids - modular residential buildings. The genesis and history of modular housing construction are traced. The advantages and problems of modular housing construction are determined. The study identified modern trends in modular construction: 1) the desire for maximum consolidation of construction ...
Halyna Osychenko, Natalia Kryvoruchko, Olha Shushliakova   +2 more
openaire   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Design Strategies for Modular Demountable Building Products Oriented to Design for Manufacturing and Assembly: A Case Study of M-Box1.0

Buildings
With the advancement of building industrialization and sustainable development, modular demountable buildings, as an efficient and environmentally friendly form, show significant potential in scenarios such as emergency housing and rural construction ...
Meng Wang, Yifan Jing, Jianghua Wang, Pawel Mika, Feng Li, Yikang Yan   +5 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Evaluating Modular House Construction Projects: A Delphi Method Enhanced by Conversational AI

Buildings
This study focuses on evaluating modular house construction projects, which is a critical segment within sustainable building practices. Despite the significant advantages of modular construction, such as enhanced resource efficiency and reduced ...
Augustinas Maceika, Andrej Bugajev, Olga R. Šostak   +2 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Selection of Renewable Energy Sources for Modular and Mobile “Green Classroom” Facilities

Energies
This article aims to demonstrate the technical capabilities and effectiveness of an energy production and management system for school facilities using a modular solution. The system is assumed to generate electricity from renewable sources, such as wind
Tomasz Węgiel, Dariusz Borkowski, Rafał Blazy, Agnieszka Ciepiela, Mariusz Łysień, Jakub Dudek, Jakub Błachut, Hanna Hrehorowicz-Gaber, Alicja Hrehorowicz-Nowak   +8 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source