Results 61 to 70 of about 3,246,445 (295)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Variable discrimination of crossover versus mutation using parameterized modular structure

, 2007
Recent work has provided functions that can be used to prove a principled distinction between the capabilities of mutation-based and crossover-based algorithms.
Richard A. Watson, Rob Mills, Mills, Rob, Watson, Richard A.   +3 more
core   +2 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Design Strategies for Modular Demountable Building Products Oriented to Design for Manufacturing and Assembly: A Case Study of M-Box1.0

Buildings
With the advancement of building industrialization and sustainable development, modular demountable buildings, as an efficient and environmentally friendly form, show significant potential in scenarios such as emergency housing and rural construction ...
Meng Wang, Yifan Jing, Jianghua Wang, Pawel Mika, Feng Li, Yikang Yan   +5 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Towards Greener Tourism: Evaluation of the Energy Performance and Self-Sufficiency in a Modular Dwelling Across Spanish Territory

Buildings
Repurposing shipping containers to construct modular buildings is an emerging trend that contributes to a more sustainable building sector. In the tourism sector, they enable low-impact, relocatable accommodation adaptable to diverse environments ...
Javier López-Bértolo, Raquel Pérez-Orozco, Moisés Cordeiro-Costas, Pablo López-Araújo, Pablo Eguía-Oller   +4 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Modular Building Advisory Board Meeting

, 2010
Modular Building Board meeting minutes for Mar ...
Building Safety, Idaho Div. of;
core  

Habitação de interesse social em madeira conforme os princípios de coordenação modular e conectividade [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnologico, Programa de Pós-graduação em Engenharia Civil, Florianópolis, 2010O Brasil, atualmente, apresenta uma crescente área de florestas plantadas, que pode ser aplicada de ...
Espíndola, Luciana da Rosa
core  

Idaho Modular Building Advisory Board Meeting

, 2008
Modular Building Advisory Board meeting minutes for Dec ...
Building Safety, Idaho Div. of;
core   +1 more source