Results 51 to 60 of about 47,821 (265)

Theoretical and Simulation-Based Approach to BIPV Systems Integrated with Modular Building

Energies
This study presents a simulation-based analysis of a steel modular building that integrates technologies that support the energy transition in the built environment.
Julia Brenk, Barbara Ksit, Bożena Orlik-Kożdoń   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Design Strategies for Modular Demountable Building Products Oriented to Design for Manufacturing and Assembly: A Case Study of M-Box1.0

Buildings
With the advancement of building industrialization and sustainable development, modular demountable buildings, as an efficient and environmentally friendly form, show significant potential in scenarios such as emergency housing and rural construction ...
Meng Wang, Yifan Jing, Jianghua Wang, Pawel Mika, Feng Li, Yikang Yan   +5 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Towards Greener Tourism: Evaluation of the Energy Performance and Self-Sufficiency in a Modular Dwelling Across Spanish Territory

Buildings
Repurposing shipping containers to construct modular buildings is an emerging trend that contributes to a more sustainable building sector. In the tourism sector, they enable low-impact, relocatable accommodation adaptable to diverse environments ...
Javier López-Bértolo, Raquel Pérez-Orozco, Moisés Cordeiro-Costas, Pablo López-Araújo, Pablo Eguía-Oller   +4 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Performance Evaluation of Architectural Modular Member with Ultra-High-Performance Fiber-Reinforced Concrete for Application

Applied Sciences
As the modular industry expands, the most widely used building materials are primarily concrete, steel, and wood. However, the use of wood and steel is severely limited compared to concrete for reasons such as durability and economy.
Kyongchul Kim, Yongsik Yoon, Gumsung Ryu, Kyungtaek Koh, Kwangmo Lim   +4 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Evaluating Modular House Construction Projects: A Delphi Method Enhanced by Conversational AI

Buildings
This study focuses on evaluating modular house construction projects, which is a critical segment within sustainable building practices. Despite the significant advantages of modular construction, such as enhanced resource efficiency and reduced ...
Augustinas Maceika, Andrej Bugajev, Olga R. Šostak   +2 more
doaj   +1 more source