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Modular houses as a form of sustainable construction
Budownictwo o Zoptymalizowanym Potencjale Energetycznym, 2023 The article discusses the currently developing technology for building economical and energy-saving modular houses. Based on the literature analysis of historical and new modular construction solutions, an attempt was made to classify modular houses and ...
Andrzej Kysiak, Bogusław Szuba
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Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Modular Games for Coalgebraic Fixed Point Logics [PDF]
, 2008 We build on existing work on finitary modular coalgebraic logics [3,4], which we extend with general fixed points, including CTL- and PDL-like fixed points, and modular evaluation games.
Sadrzadeh, Mehrnoosh, Cirstea, Corina
core +2 more sources
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Supporting 'design for reuse' with modular design [PDF]
, 2007 Engineering design reuse refers to the utilization of any knowledge gained from the design activity to support future design. As such, engineering design reuse approaches are concerned with the support, exploration, and enhancement of design knowledge ...
Meehan, J.S. +2 more
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Theoretical and Simulation-Based Approach to BIPV Systems Integrated with Modular Building
EnergiesThis study presents a simulation-based analysis of a steel modular building that integrates technologies that support the energy transition in the built environment.
Julia Brenk +2 more
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Advances in Materials Science and Engineering, 2018 Modular prefabricated buildings effectively improve the efficiency and quality of building design and construction and represent an important trend in the development of building industrialization. However, there are still many deficiencies in the design
Junjie Li +5 more
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