Results 81 to 90 of about 389,954 (327)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
From Holonomy of the Ising Model Form Factors to n-Fold Integrals and the Theory of Elliptic Curves
Symmetry, Integrability and Geometry: Methods and Applications, 2007 We recall the form factors $f^(j)_{N,N}$ corresponding to the $lambda$-extension $C(N,N; lambda)$ of the two-point diagonal correlation function of the Ising model on the square lattice and their associated linear differential equations which exhibit ...
Salah Boukraa +3 more
doaj
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Computing Classical Modular Forms
, 2021 63 pages; minor edits, including a correction to Conjecture 8.5 ...
Best, Alex +10 more
openaire +4 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
From modular graph forms to iterated integrals
Journal of High Energy PhysicsModular graph forms are a class of non-holomorphic modular forms that arise in the low-energy expansion of genus-one closed string amplitudes. In this work, we introduce a systematic procedure to convert lattice-sum representations of modular graph forms
E. Claasen, M. Doroudiani
doaj +1 more source
New A 4 lepton flavor model from S 4 modular symmetry
Journal of High Energy Physics, 2020 We study a flavor model with A 4 symmetry which originates from S 4 modular group. In S 4 symmetry, Z 2 subgroup can be anomalous, and then S 4 can be violated to A 4.
Tatsuo Kobayashi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Modular forms for three-loop banana integrals
Journal of High Energy PhysicsWe study periods of multi-parameter families of K3 surfaces, which are relevant to compute the maximal cuts of certain classes of Feynman integrals. We focus on their automorphic properties, and we show that generically the periods define orthogonal ...
Claude Duhr
doaj +1 more source
Siegel modular forms and black hole entropy
Journal of High Energy Physics, 2017 We discuss the application of Siegel Modular Forms to Black Hole entropy counting. The role of the Igusa cusp form χ 10 in the D1D5P system is well-known, and its transformation properties are what allows precision microstate counting in this case.
Alexandre Belin +3 more
doaj +1 more source