Results 61 to 70 of about 10,760,607 (302)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Effect of disconnection of deformable units on the mobility and stiffness of 3D prismatic modular origami structures using angular kinematics

Scientific Reports, 2021
Architected modular origami structures show potential for future robotic matter owing to their reconfigurability with multiple mobilities. Similar to modular robots, the units of modular origami structures do not need to be assembled in a fully packed ...
Kai Xiao, Xiang Zhou, Jaehyung Ju
doaj   +1 more source

Banach operator pairs and common fixed points in modular function spaces

, 2011
In this article, we introduce the concept of a Banach operator pair in the setting of modular function spaces. We prove some common fixed point results for such type of operators satisfying a more general condition of nonexpansiveness.
N. Hussain, M. Khamsi, A. Latif
semanticscholar   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Preliminary structural design method for modular wing

Hangkong gongcheng jinzhan
Aircraft modular design can increase the types of missions and reduce costs. In the initial stage of wing modular structure design，the unclearness of wingtip deformation limits the ability to assess the contribution differences of structural stiffness ...
FAN Fulei, LI Yi, CHEN Chunying, JIA Zhaohu   +3 more
doaj   +1 more source

Congruences for coefficients of modular functions [PDF]

, 2022
Paul M. Jenkins, DJ Thornton
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Mechanisms of Change: A Population-Based Perspective on the Roles of Modularity and Pleiotropy in Diversification

Frontiers in Ecology and Evolution, 2020
Developmental modularity has long been viewed as a hierarchical organization that facilitates evolution through modification or reuse of preexisting modules.
James J. Lewis, Steven M. Van Belleghem
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Lessons from the Ramond sector

SciPost Physics, 2020
We revisit the consistency of torus partition functions in (1+1)$d$ fermionic conformal field theories, combining traditional ingredients of modular invariance/covariance with a modernized understanding of bosonization/fermionization dualities.
Nathan Benjamin, Ying-Hsuan Lin
doaj   +1 more source