Results 31 to 40 of about 59,609 (323)

Modular Composition of Synthetic Biology Designs using Rule-Based Models [PDF]

open access: green, 2016
Göksel Mısırlı   +5 more
openalex   +1 more source

Module detection in complex networks using integer optimisation

open access: yesAlgorithms for Molecular Biology, 2010
Background The detection of modules or community structure is widely used to reveal the underlying properties of complex networks in biology, as well as physical and social sciences.
Tsoka Sophia   +3 more
doaj   +1 more source

The taming of the neural crest: a developmental perspective on the origins of morphological covariation in domesticated mammals [PDF]

open access: yesRoyal Society Open Science, 2016
Studies on domestication are blooming, but the developmental bases for the generation of domestication traits and breed diversity remain largely unexplored.
Marcelo R. Sánchez-Villagra   +2 more
doaj   +1 more source

Grounding knowledge and normative valuation in agent-based action and scientific commitment [PDF]

open access: yes, 2018
Philosophical investigation in synthetic biology has focused on the knowledge-seeking questions pursued, the kind of engineering techniques used, and on the ethical impact of the products produced.
A Clark   +50 more
core   +1 more source

Modular cell biology: retroactivity and insulation

open access: yesMolecular Systems Biology, 2008
Modularity plays a fundamental role in the prediction of the behavior of a system from the behavior of its components, guaranteeing that the properties of individual components do not change upon interconnection. Just as electrical, hydraulic, and other physical systems often do not display modularity, nor do many biochemical systems, and specifically,
Del Vecchio, Domitilla   +2 more
openaire   +4 more sources

Modular Verification of Interactive Systems with an Application to Biology

open access: greenElectronic Notes in Theoretical Computer Science, 2011
We propose sync-programs, an automata-based formalism for the description of biological systems, and a modular verification technique for such a formalism that allows properties expressed in the universal fragment of CTL to be verified on suitably chosen fragments of models, rather than on whole models.
Peter Drábik   +2 more
openalex   +5 more sources

On the role of sparseness in the evolution of modularity in gene regulatory networks.

open access: yesPLoS Computational Biology, 2018
Modularity is a widespread property in biological systems. It implies that interactions occur mainly within groups of system elements. A modular arrangement facilitates adjustment of one module without perturbing the rest of the system.
Carlos Espinosa-Soto
doaj   +1 more source

Optimizing Calcium Detection Methods in Animal Systems: A Sandbox for Synthetic Biology

open access: yesBiomolecules, 2021
Since the 1970s, the emergence and expansion of novel methods for calcium ion (Ca2+) detection have found diverse applications in vitro and in vivo across a series of model animal systems.
Elizabeth S. Li, Margaret S. Saha
doaj   +1 more source

A citation-based map of concepts in invasion biology [PDF]

open access: yes, 2019
Invasion biology has been quickly expanding in the last decades so that it is now metaphorically flooded with publications, concepts, and hypotheses. Among experts, there is no clear consensus about the relationships between invasion concepts, and almost
Enders, Martin   +2 more
core   +1 more source

Computer-Aided Whole-Cell Design: Taking a Holistic Approach by Integrating Synthetic With Systems Biology

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Computer-aided design (CAD) for synthetic biology promises to accelerate the rational and robust engineering of biological systems. It requires both detailed and quantitative mathematical and experimental models of the processes to (re)design biology ...
Lucia Marucci   +23 more
doaj   +1 more source

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