Results 41 to 50 of about 59,609 (323)
The dichotomy in degree correlation of biological networks. [PDF]
PLoS ONE, 2011 Most complex networks from different areas such as biology, sociology or technology, show a correlation on node degree where the possibility of a link between two nodes depends on their connectivity. It is widely believed that complex networks are either
Dapeng Hao, Chuanxing Li
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DISTILLER: a data integration framework to reveal condition dependency of complex regulons in Escherichia coli [PDF]
, 2009 We present DISTILLER, a data integration framework for the inference of transcriptional module networks. Experimental validation of predicted targets for the well-studied fumarate nitrate reductase regulator showed the effectiveness of our approach in ...
Lemmens, Karen +11 more
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Toolbox for Exploring Modular Gene Regulation in Synthetic Biology Training [PDF]
ACS Synthetic Biology, 2016 We report a toolbox for exploring the modular tuning of genetic circuits, which has been specifically optimized for widespread deployment in STEM environments through a combination of bacterial strain engineering and distributable hardware development.
Magaraci, Michael S +8 more
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Life’s building blocks: the modular path to multiscale complexity
Frontiers in Systems BiologyModularity, the structuring of systems into discrete, interconnected units, is a fundamental organizing principle in biology across multiple scales. Recent progress in understanding the role of modularity as an evolutionary mechanism and a key driver of ...
Saúl Huitzil +4 more
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Modularity Enhances the Rate of Evolution in a Rugged Fitness Landscape
, 2015 Biological systems are modular, and this modularity affects the evolution of biological systems over time and in different environments. We here develop a theory for the dynamics of evolution in a rugged, modular fitness landscape.
Chen, Man +3 more
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Modularity and the spread of perturbations in complex dynamical systems [PDF]
, 2015 We propose a method to decompose dynamical systems based on the idea that modules constrain the spread of perturbations. We find partitions of system variables that maximize 'perturbation modularity', defined as the autocovariance of coarse-grained ...
Gates, Alexander J. +2 more
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Does modularity undermine the pro‐emotion consensus? [PDF]
, 2020 There is a growing consensus that emotions contribute positively to human practical rationality. While arguments that defend this position often appeal to the modularity of emotion-generation mechanisms, these arguments are also susceptible to the ...
Majeed, Raamy
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Bottom-up synthetic biology: modular design for making artificial platelets [PDF]
Physical Biology, 2017 Engineering artificial cells to mimic one or multiple fundamental cell biological functions is an emerging area of synthetic biology. Reconstituting functional modules from biological components in vitro is a challenging yet an important essence of bottom-up synthetic biology.
Sagardip Majumder, Allen P Liu
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Reengineering Metaphysics: Modularity, Parthood, and Evolvability in Metabolic Engineering
Philosophy, Theory, and Practice in Biology, 2017 The premise of biological modularity is an ontological claim that appears to come out of practice. We understand that the biological world is modular because we can manipulate different parts of organisms in ways that would only work if there were ...
Catherine Kendig, Todd T. Eckdahl
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Refining modules to determine functionally significant clusters in molecular networks
BMC Genomics, 2019 Background Module detection algorithms relying on modularity maximization suffer from an inherent resolution limit that hinders detection of small topological modules, especially in molecular networks where most biological processes are believed to form ...
Rama Kaalia, Jagath C. Rajapakse
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