Results 111 to 120 of about 766,195 (336)

Role of TREK-1 in Health and Disease, Focus on the Central Nervous System

open access: yesFrontiers in Pharmacology, 2019
TREK-1 is the most studied background K2P channel. Its main role is to control cell excitability and maintain the membrane potential below the threshold of depolarization.
Alaeddine Djillani   +3 more
doaj   +1 more source

[Corrigendum] Cyclophilin D modulates cell death transition from early apoptosis to programmed necrosis induced by honokiol

open access: hybrid, 2021
Wei Tian   +8 more
openalex   +2 more sources

Koszul Modules

open access: yesJournal of Pure and Applied Algebra, 2005
From the authors' introduction: Consider a noetherian local ring \(R\) with maximal ideal \(\mathcal M\) and residue field \(k\). Given a finitely generated \(R\)-module \(M\) and \(F\) its minimal free resolution, denote \(\text{lin}^R(F)\) the associated graded complex of \(F\) arising from the standard \(\mathcal M\)-adic filtration.
Herzog, Jürgen, Iyengar, Srikanth
openaire   +2 more sources

60 GHz and 94 GHz antenna-coupled LiNbO_3 electrooptic modulators [PDF]

open access: yes, 1993
Antenna-coupled LiBbO_3 electrooptic modulators can overcome the material dispersion which would otherwise prevent sensitive high-frequency operation. The authors previously demonstrated the concept with a phase modulator at X-band.
Bridges, William B.   +2 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Optically induced free carrier light modulator [PDF]

open access: yes, 1969
Signal carrier laser beam is optically modulated by a second laser beam of different frequency acting on a free carrier source to which the signal carrier laser is directed.
Gruber, C. L., Richards, W. E.
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Coupled Bilayer Photonic Crystal Slab Electro-Optic Spatial Light Modulators

open access: yesIEEE Photonics Journal, 2017
We demonstrate here a surface-normal ultracompact Fano resonance electro-optic spatial light modulator employing a stacked photonic crystal membrane capacitor-like structure.
Yi-Chen Shuai   +5 more
doaj   +1 more source

Novel polyhydroxyalkanoate beads for use as a vaccine against tuberculosis : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Microbiology at Massey University, Manawatū, New Zealand [PDF]

open access: yes, 2017
Tuberculosis was in 1993 declared as a re-emerging disease by the World Health Organization. The only vaccine currently available, BCG, an attenuated strain of Mycobacterium bovis, does not protect adults against the pulmonary disease, which is the ...
Rubio Reyes, Patricia
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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