Results 111 to 120 of about 6,155,889 (255)

Crop DNA extraction with lab-made magnetic nanoparticles.

PLoS ONE
Molecular breeding methods, such as marker-assisted selection and genomic selection, require high-throughput and cost-effective methods for isolating genomic DNA from plants, specifically from crop tissue or seed with high polysaccharides, lipids, and ...
Haichuan Wang, Xueqi Zhao, Li Tan, Junwei Zhu, David Hyten   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Molecular markers for the identification of resistance genes and marker-assisted selection in breeding wheat for leaf rust resistance

, 2009
The resistance genes Lr9, Lr24, Lr25, Lr29, Lr35 and Lr37, which were not previously utilised in Hungary, have been incorporated into four Martonvasar winter wheat cultivars using marker-assisted selection with PCR-based markers.
Uhrin, Andrea, Vida, G., Veisz, Otto, Bedo, Zoltan, Uhrin, A., Flavell, A., Bedő, Z., Flavell, Andrew J., Gál, M., Vida, Gyula, Syed, N., Wang, Zhulin, Wang, Z., Gal, Mariann, Hasan-Syed, Naeem, Veisz, O.   +15 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Other title: Title from HTML header (viewed Nov. 9, 2011): Judicial Selection Commission

, 2013
Updated irregularly; Began in 2002?; Title from main search screen (publisher's Web site, viewed Nov. 9, 2011).; At head of title: State of Connecticut.; Harvested from the web on 3/13/13Official website of the Connecticut Judicial Selection Commission ...

core  

Managing diversity in practical ambient assisted living ecosystems [PDF]

, 2010
Poster presentation at the AALIANCE Conference, Malaga, Spain, March, 11-12 2010Though the motivation for developing ambient assisted living (AAL) systems is incontestable, significant challenges exist in realizing the ambience that is essential to the ...
O'Grady, Michael, Dragone, Mauro; id_orcid, O\u27Grady, Michael, O'Hare, G. M. P. (Greg M. P.), O\u27Grady, Michael J., O\u27Hare, Gregory M.P., O’Grady, Michael J., O'Hare, Gregory M.P., O'Hare, Gregory M. P., Gurrin, Cathal, O'Grady, Michael J., Tynan, Richard, Dragone, Mauro, Walsh, Michael, O\u27Hare, G. M. P. (Greg M. P.)   +14 more
core   +1 more source

Towards sustainable use of acidic soils: Deciphering aluminum-resistant mechanisms in plants

Fundamental Research
The widespread occurrence of acidic soils presents a major challenge for agriculture, as it hampers productivity via a combination of mineral toxicity, nutrient deficiency, and poor water uptake.
Xiao Fang Zhu, Ren Fang Shen
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Development of aromatic giant-embryo rice by molecular marker-assisted selection

上海师范大学学报. 自然科学版, 2013
Aromatic rice is loved for its distinctive aroma when cooking and eating.In this research,aromatic normal-embryo rice and non-aromatic giant-embryo rice,"Shangshida No.5",both bred by our laboratory,were selected as the parents for the hybridization.We ...
ZHU Yingdong, SHI Yaqiong, ZHOU Fengli, LI Jianyue   +3 more
doaj  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source